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Oxytocin is an anabolic bone hormone.
Tamma R, Colaianni G, Zhu LL, DiBenedetto A, Greco G, Montemurro G, Patano N, Strippoli M, Vergari R, Mancini L, Colucci S, Grano M, Faccio R, Liu X, Li J, Usmani S, Bachar M, Bab I, Nishimori K, Young LJ, Buettner C, Iqbal J, Sun L, Zaidi M, Zallone A. Tamma R, et al. Among authors: dibenedetto a. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7149-54. doi: 10.1073/pnas.0901890106. Epub 2009 Apr 15. Proc Natl Acad Sci U S A. 2009. PMID: 19369205 Free PMC article.
The oxytocin-bone axis.
Colaianni G, Tamma R, Di Benedetto A, Yuen T, Sun L, Zaidi M, Zallone A. Colaianni G, et al. J Neuroendocrinol. 2014 Feb;26(2):53-7. doi: 10.1111/jne.12120. J Neuroendocrinol. 2014. PMID: 24219627 Free PMC article. Review.
Regulated production of the pituitary hormone oxytocin from murine and human osteoblasts.
Colaianni G, Di Benedetto A, Zhu LL, Tamma R, Li J, Greco G, Peng Y, Dell'Endice S, Zhu G, Cuscito C, Grano M, Colucci S, Iqbal J, Yuen T, Sun L, Zaidi M, Zallone A. Colaianni G, et al. Biochem Biophys Res Commun. 2011 Aug 5;411(3):512-5. doi: 10.1016/j.bbrc.2011.06.158. Epub 2011 Jun 29. Biochem Biophys Res Commun. 2011. PMID: 21741363
Adrenergic stimulation decreases osteoblast oxytocin synthesis.
Cuscito C, Colaianni G, Tamma R, Greco G, Dell'Endice S, Yuen T, Sun L, Zaidi M, Di Benedetto A, Zallone A. Cuscito C, et al. Ann N Y Acad Sci. 2011 Nov;1237:53-7. doi: 10.1111/j.1749-6632.2011.06235.x. Ann N Y Acad Sci. 2011. PMID: 22082365
Regulation of bone remodeling by vasopressin explains the bone loss in hyponatremia.
Tamma R, Sun L, Cuscito C, Lu P, Corcelli M, Li J, Colaianni G, Moonga SS, Di Benedetto A, Grano M, Colucci S, Yuen T, New MI, Zallone A, Zaidi M. Tamma R, et al. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18644-9. doi: 10.1073/pnas.1318257110. Epub 2013 Oct 28. Proc Natl Acad Sci U S A. 2013. PMID: 24167258 Free PMC article.
Osteoblast regulation via ligand-activated nuclear trafficking of the oxytocin receptor.
Di Benedetto A, Sun L, Zambonin CG, Tamma R, Nico B, Calvano CD, Colaianni G, Ji Y, Mori G, Grano M, Lu P, Colucci S, Yuen T, New MI, Zallone A, Zaidi M. Di Benedetto A, et al. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16502-7. doi: 10.1073/pnas.1419349111. Epub 2014 Nov 5. Proc Natl Acad Sci U S A. 2014. PMID: 25378700 Free PMC article.
The myokine irisin increases cortical bone mass.
Colaianni G, Cuscito C, Mongelli T, Pignataro P, Buccoliero C, Liu P, Lu P, Sartini L, Di Comite M, Mori G, Di Benedetto A, Brunetti G, Yuen T, Sun L, Reseland JE, Colucci S, New MI, Zaidi M, Cinti S, Grano M. Colaianni G, et al. Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12157-62. doi: 10.1073/pnas.1516622112. Epub 2015 Sep 15. Proc Natl Acad Sci U S A. 2015. PMID: 26374841 Free PMC article.
Functions of vasopressin and oxytocin in bone mass regulation.
Sun L, Tamma R, Yuen T, Colaianni G, Ji Y, Cuscito C, Bailey J, Dhawan S, Lu P, Calvano CD, Zhu LL, Zambonin CG, Di Benedetto A, Stachnik A, Liu P, Grano M, Colucci S, Davies TF, New MI, Zallone A, Zaidi M. Sun L, et al. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):164-9. doi: 10.1073/pnas.1523762113. Epub 2015 Dec 22. Proc Natl Acad Sci U S A. 2016. PMID: 26699482 Free PMC article.
TRAIL is involved in human osteoclast apoptosis.
Brunetti G, Oranger A, Mori G, Tamma R, Di Benedetto A, Pignataro P, Grassi FR, Zallone A, Grano M, Colucci S. Brunetti G, et al. Ann N Y Acad Sci. 2007 Nov;1116:316-22. doi: 10.1196/annals.1402.011. Epub 2007 Jun 21. Ann N Y Acad Sci. 2007. PMID: 17584981
145 results