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Targeted systematic evolution of an RNA platform neutralizing DNMT1 function and controlling DNA methylation.
Esposito CL, Autiero I, Sandomenico A, Li H, Bassal MA, Ibba ML, Wang D, Rinaldi L, Ummarino S, Gaggi G, Borchiellini M, Swiderski P, Ruvo M, Catuogno S, Ebralidze AK, Kortylewski M, de Franciscis V, Di Ruscio A. Esposito CL, et al. Among authors: di ruscio a. Nat Commun. 2023 Jan 6;14(1):99. doi: 10.1038/s41467-022-35222-4. Nat Commun. 2023. PMID: 36609400 Free PMC article.
Dissecting the role of aberrant DNA methylation in human leukaemia.
Amabile G, Di Ruscio A, Müller F, Welner RS, Yang H, Ebralidze AK, Zhang H, Levantini E, Qi L, Martinelli G, Brummelkamp T, Le Beau MM, Figueroa ME, Bock C, Tenen DG. Amabile G, et al. Among authors: di ruscio a. Nat Commun. 2015 May 22;6:7091. doi: 10.1038/ncomms8091. Nat Commun. 2015. PMID: 25997600 Free PMC article.
The PARP Way to Epigenetic Changes.
Ummarino S, Hausman C, Di Ruscio A. Ummarino S, et al. Among authors: di ruscio a. Genes (Basel). 2021 Mar 20;12(3):446. doi: 10.3390/genes12030446. Genes (Basel). 2021. PMID: 33804735 Free PMC article. Review.
NAD Modulates DNA Methylation and Cell Differentiation.
Ummarino S, Hausman C, Gaggi G, Rinaldi L, Bassal MA, Zhang Y, Seelam AJ, Kobayashi IS, Borchiellini M, Ebralidze AK, Ghinassi B, Trinh BQ, Kobayashi SS, Di Ruscio A. Ummarino S, et al. Among authors: di ruscio a. Cells. 2021 Nov 2;10(11):2986. doi: 10.3390/cells10112986. Cells. 2021. PMID: 34831209 Free PMC article.
Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases.
Canesin G, Di Ruscio A, Li M, Ummarino S, Hedblom A, Choudhury R, Krzyzanowska A, Csizmadia E, Palominos M, Stiehm A, Ebralidze A, Chen SY, Bassal MA, Zhao P, Tolosano E, Hurley L, Bjartell A, Tenen DG, Wegiel B. Canesin G, et al. Among authors: di ruscio a. Cell Rep. 2020 Sep 22;32(12):108181. doi: 10.1016/j.celrep.2020.108181. Cell Rep. 2020. PMID: 32966797 Free PMC article.
Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML.
Trinh BQ, Ummarino S, Zhang Y, Ebralidze AK, Bassal MA, Nguyen TM, Heller G, Coffey R, Tenen DE, van der Kouwe E, Fabiani E, Gurnari C, Wu CS, Angarica VE, Yang H, Chen S, Zhang H, Thurm AR, Marchi F, Levantini E, Staber PB, Zhang P, Voso MT, Pandolfi PP, Kobayashi SS, Chai L, Di Ruscio A, Tenen DG. Trinh BQ, et al. Among authors: di ruscio a. Blood. 2021 Oct 14;138(15):1331-1344. doi: 10.1182/blood.2020007920. Blood. 2021. PMID: 33971010 Free PMC article.
Epigenetic Features of Human Perinatal Stem Cells Redefine Their Stemness Potential.
Gaggi G, Di Credico A, Izzicupo P, Antonucci I, Crescioli C, Di Giacomo V, Di Ruscio A, Amabile G, Alviano F, Di Baldassarre A, Ghinassi B. Gaggi G, et al. Among authors: di credico a, di ruscio a, di giacomo v, di baldassarre a. Cells. 2020 May 24;9(5):1304. doi: 10.3390/cells9051304. Cells. 2020. PMID: 32456308 Free PMC article.
Pseudogene-mediated DNA demethylation leads to oncogene activation.
Kwon J, Liu YV, Gao C, Bassal MA, Jones AI, Yang J, Chen Z, Li Y, Yang H, Chen L, Di Ruscio A, Tay Y, Chai L, Tenen DG. Kwon J, et al. Among authors: di ruscio a. Sci Adv. 2021 Oct;7(40):eabg1695. doi: 10.1126/sciadv.abg1695. Epub 2021 Oct 1. Sci Adv. 2021. PMID: 34597139 Free PMC article.
41 results