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A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiency.
Tamma G, Lasorsa D, Trimpert C, Ranieri M, Di Mise A, Mola MG, Mastrofrancesco L, Devuyst O, Svelto M, Deen PM, Valenti G. Tamma G, et al. Among authors: di mise a. J Am Soc Nephrol. 2014 Oct;25(10):2241-53. doi: 10.1681/ASN.2013111234. Epub 2014 Apr 3. J Am Soc Nephrol. 2014. PMID: 24700872 Free PMC article.
CaSR signaling down-regulates AQP2 expression via a novel microRNA pathway in pendrin and NaCl cotransporter knockout mice.
Ranieri M, Zahedi K, Tamma G, Centrone M, Di Mise A, Soleimani M, Valenti G. Ranieri M, et al. Among authors: di mise a. FASEB J. 2018 Apr;32(4):2148-2159. doi: 10.1096/fj.201700412RR. Epub 2018 Jan 5. FASEB J. 2018. PMID: 29212817
These effects may contribute to the reduced renal concentrating ability that has been observed in dKO mice and underscore a physiologic mechanism of the CaSR-dependent regulation of AQP2 abundance via a novel microRNA pathway.-Ranieri, M., Zahedi, K., Tamma, G., Cen …
These effects may contribute to the reduced renal concentrating ability that has been observed in dKO mice and underscore a physiolog …
Gain-of-function mutations of the V2 vasopressin receptor in nephrogenic syndrome of inappropriate antidiuresis (NSIAD): a cell-based assay to assess constitutive water reabsorption.
Ranieri M, Tamma G, Pellegrino T, Vezzi V, Ambrosio C, Grò C, Di Mise A, Costa T, Valenti G, Cotecchia S. Ranieri M, et al. Among authors: di mise a. Pflugers Arch. 2019 Oct;471(10):1291-1304. doi: 10.1007/s00424-019-02307-x. Epub 2019 Sep 5. Pflugers Arch. 2019. PMID: 31486901
The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation.
Ranieri M, Venneri M, Pellegrino T, Centrone M, Di Mise A, Cotecchia S, Tamma G, Valenti G. Ranieri M, et al. Among authors: di mise a. Cells. 2020 May 29;9(6):1354. doi: 10.3390/cells9061354. Cells. 2020. PMID: 32486031 Free PMC article.
38 results