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Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors.
Bonandi E, Mori M, Infante P, Basili I, Di Marcotullio L, Calcaterra A, Catti F, Botta B, Passarella D. Bonandi E, et al. Among authors: di marcotullio l. Chemistry. 2021 Jun 4;27(32):8350-8357. doi: 10.1002/chem.202100315. Epub 2021 May 4. Chemistry. 2021. PMID: 33811701 Free PMC article.
Hedgehog signaling pathway in neural development and disease.
Gulino A, Di Marcotullio L, Ferretti E, De Smaele E, Screpanti I. Gulino A, et al. Among authors: di marcotullio l. Psychoneuroendocrinology. 2007 Aug;32 Suppl 1:S52-6. doi: 10.1016/j.psyneuen.2007.03.017. Epub 2007 Jul 9. Psychoneuroendocrinology. 2007. PMID: 17619088 Review.
Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.
Canettieri G, Di Marcotullio L, Greco A, Coni S, Antonucci L, Infante P, Pietrosanti L, De Smaele E, Ferretti E, Miele E, Pelloni M, De Simone G, Pedone EM, Gallinari P, Giorgi A, Steinkühler C, Vitagliano L, Pedone C, Schinin ME, Screpanti I, Gulino A. Canettieri G, et al. Among authors: di marcotullio l. Nat Cell Biol. 2010 Feb;12(2):132-42. doi: 10.1038/ncb2013. Epub 2010 Jan 17. Nat Cell Biol. 2010. PMID: 20081843
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.
De Smaele E, Di Marcotullio L, Moretti M, Pelloni M, Occhione MA, Infante P, Cucchi D, Greco A, Pietrosanti L, Todorovic J, Coni S, Canettieri G, Ferretti E, Bei R, Maroder M, Screpanti I, Gulino A. De Smaele E, et al. Among authors: di marcotullio l. Neoplasia. 2011 Apr;13(4):374-85. doi: 10.1593/neo.101630. Neoplasia. 2011. PMID: 21472142 Free PMC article.
Hedgehog/Gli control by ubiquitination/acetylation interplay.
Gulino A, Di Marcotullio L, Canettieri G, De Smaele E, Screpanti I. Gulino A, et al. Among authors: di marcotullio l. Vitam Horm. 2012;88:211-27. doi: 10.1016/B978-0-12-394622-5.00009-2. Vitam Horm. 2012. PMID: 22391305 Review.
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress.
Mazzà D, Infante P, Colicchia V, Greco A, Alfonsi R, Siler M, Antonucci L, Po A, De Smaele E, Ferretti E, Capalbo C, Bellavia D, Canettieri G, Giannini G, Screpanti I, Gulino A, Di Marcotullio L. Mazzà D, et al. Among authors: di marcotullio l. Cell Death Differ. 2013 Dec;20(12):1688-97. doi: 10.1038/cdd.2013.120. Epub 2013 Sep 6. Cell Death Differ. 2013. PMID: 24013724 Free PMC article.
102 results