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Promoting active site renewal in heterogeneous olefin metathesis catalysts.
Gani TZH, Berkson ZJ, Zhu R, Kang JH, Di Iorio JR, Chan KW, Consoli DF, Shaikh SK, Copéret C, Román-Leshkov Y. Gani TZH, et al. Among authors: di iorio jr. Nature. 2023 May;617(7961):524-528. doi: 10.1038/s41586-023-05897-w. Epub 2023 May 17. Nature. 2023. PMID: 37198312
Flavonoid Derivatives as New Potent Inhibitors of Cysteine Proteases: An Important Step toward the Design of New Compounds for the Treatment of Leishmaniasis.
Lourenço EMG, Di Iório JF, da Silva F, Fialho FLB, Monteiro MM, Beatriz A, Perdomo RT, Barbosa EG, Oses JP, de Arruda CCP, de Souza Júdice WA, Rafique J, de Lima DP. Lourenço EMG, et al. Among authors: di iorio jf. Microorganisms. 2023 Jan 16;11(1):225. doi: 10.3390/microorganisms11010225. Microorganisms. 2023. PMID: 36677517 Free PMC article.
Semysinthetic biflavonoid Morelloflavone-7,4',7″,3‴,4‴-penta-O-butanoyl is a more potent inhibitor of Proprotein Convertases Subtilisin/Kexin PC1/3 than Kex2 and Furin.
de Souza AA, de Andrade DM, Siqueira FDS, Di Iorio JF, Veloso MP, Coelho CM, Viegas Junior C, Gontijo VS, Dos Santos MH, Meneghetti MCZ, Nader HB, Tersariol ILDS, Juliano L, Juliano MA, Judice WAS. de Souza AA, et al. Among authors: di iorio jf. Biochim Biophys Acta Gen Subj. 2021 Dec;1865(12):130016. doi: 10.1016/j.bbagen.2021.130016. Epub 2021 Sep 22. Biochim Biophys Acta Gen Subj. 2021. PMID: 34560176
Cysteine proteases as potential targets for anti-trypanosomatid drug discovery.
Judice WAS, Ferraz LS, Lopes RM, Vianna LDS, Siqueira FDS, Di Iorio JF, Dalzoto LAM, Trujilho MNR, Santos TDR, Machado MFM, Rodrigues T. Judice WAS, et al. Among authors: di iorio jf. Bioorg Med Chem. 2021 Sep 15;46:116365. doi: 10.1016/j.bmc.2021.116365. Epub 2021 Aug 13. Bioorg Med Chem. 2021. PMID: 34419821 Free article. Review.
16 results