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Optimization of Indazole-Based GSK-3 Inhibitors with Mitigated hERG Issue and In Vivo Activity in a Mood Disorder Model.
Prati F, Buonfiglio R, Furlotti G, Cavarischia C, Mangano G, Picollo R, Oggianu L, di Matteo A, Olivieri S, Bovi G, Porceddu PF, Reggiani A, Garrone B, Di Giorgio FP, Ombrato R. Prati F, et al. Among authors: di giorgio fp. ACS Med Chem Lett. 2020 Mar 24;11(5):825-831. doi: 10.1021/acsmedchemlett.9b00633. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435391 Free PMC article.
Virtual Screening Approach and Investigation of Structure-Activity Relationships To Discover Novel Bacterial Topoisomerase Inhibitors Targeting Gram-Positive and Gram-Negative Pathogens.
Magarò G, Prati F, Garofalo B, Corso G, Furlotti G, Apicella C, Mangano G, D'Atanasio N, Robinson D, Di Giorgio FP, Ombrato R. Magarò G, et al. Among authors: di giorgio fp. J Med Chem. 2019 Aug 22;62(16):7445-7472. doi: 10.1021/acs.jmedchem.9b00394. Epub 2019 Jul 31. J Med Chem. 2019. PMID: 31276392
Antibacterial activity of novel dual bacterial DNA type II topoisomerase inhibitors.
D'Atanasio N, Capezzone de Joannon A, Di Sante L, Mangano G, Ombrato R, Vitiello M, Bartella C, Magarò G, Prati F, Milanese C, Vignaroli C, Di Giorgio FP, Tongiani S. D'Atanasio N, et al. Among authors: di giorgio fp. PLoS One. 2020 Feb 19;15(2):e0228509. doi: 10.1371/journal.pone.0228509. eCollection 2020. PLoS One. 2020. PMID: 32074119 Free PMC article.
26 results