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IOA-244 is a Non-ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance.
Johnson Z, Tarantelli C, Civanelli E, Cascione L, Spriano F, Fraser A, Shah P, Nomanbhoy T, Napoli S, Rinaldi A, Niewola-Staszkowska K, Lahn M, Perrin D, Wenes M, Migliorini D, Bertoni F, van der Veen L, Di Conza G. Johnson Z, et al. Among authors: di conza g. Cancer Res Commun. 2023 Apr 14;3(4):576-591. doi: 10.1158/2767-9764.CRC-22-0477. eCollection 2023 Apr. Cancer Res Commun. 2023. PMID: 37066023 Free PMC article.
Autotaxin Secretion Is a Stromal Mechanism of Adaptive Resistance to TGFβ Inhibition in Pancreatic Ductal Adenocarcinoma.
Pietrobono S, Sabbadini F, Bertolini M, Mangiameli D, De Vita V, Fazzini F, Lunardi G, Casalino S, Scarlato E, Merz V, Zecchetto C, Quinzii A, Di Conza G, Lahn M, Melisi D. Pietrobono S, et al. Among authors: di conza g. Cancer Res. 2024 Jan 2;84(1):118-132. doi: 10.1158/0008-5472.CAN-23-0104. Cancer Res. 2024. PMID: 37738399 Free PMC article. Clinical Trial.
CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation.
Fernández-García J, Franco F, Parik S, Altea-Manzano P, Pane AA, Broekaert D, van Elsen J, Di Conza G, Vermeire I, Schalley T, Planque M, van Brussel T, Schepers R, Modave E, Karakach TK, Carmeliet P, Lambrechts D, Ho PC, Fendt SM. Fernández-García J, et al. Among authors: di conza g. Cell Rep. 2022 Nov 15;41(7):111639. doi: 10.1016/j.celrep.2022.111639. Cell Rep. 2022. PMID: 36384124 Free article.
Targeting T regulatory (Treg) cells in immunotherapy-resistant cancers.
Spiliopoulou P, Kaur P, Hammett T, Di Conza G, Lahn M. Spiliopoulou P, et al. Among authors: di conza g. Cancer Drug Resist. 2024 Jan 12;7:2. doi: 10.20517/cdr.2023.46. eCollection 2024. Cancer Drug Resist. 2024. PMID: 38318526 Free PMC article. Review.
A bioartificial and vasculomorphic bone matrix-based organoid mimicking microanatomy of flat and short bones.
Toni R, Barbaro F, Di Conza G, Zini N, Remaggi G, Elviri L, Spaletta G, Quarantini E, Quarantini M, Mosca S, Caravelli S, Mosca M, Ravanetti F, Sprio S, Tampieri A. Toni R, et al. Among authors: di conza g. J Biomed Mater Res B Appl Biomater. 2024 Jan;112(1):e35329. doi: 10.1002/jbm.b.35329. Epub 2023 Oct 29. J Biomed Mater Res B Appl Biomater. 2024. PMID: 37898921
38 results