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Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2.
Moriconi A, Cesta MC, Cervellera MN, Aramini A, Coniglio S, Colagioia S, Beccari AR, Bizzarri C, Cavicchia MR, Locati M, Galliera E, Di Benedetto P, Vigilante P, Bertini R, Allegretti M. Moriconi A, et al. Among authors: di benedetto p. J Med Chem. 2007 Aug 23;50(17):3984-4002. doi: 10.1021/jm061469t. Epub 2007 Aug 1. J Med Chem. 2007. PMID: 17665889
Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitor.
Bertini R, Barcelos LS, Beccari AR, Cavalieri B, Moriconi A, Bizzarri C, Di Benedetto P, Di Giacinto C, Gloaguen I, Galliera E, Corsi MM, Russo RC, Andrade SP, Cesta MC, Nano G, Aramini A, Cutrin JC, Locati M, Allegretti M, Teixeira MM. Bertini R, et al. Among authors: di benedetto p, di giacinto c. Br J Pharmacol. 2012 Jan;165(2):436-54. doi: 10.1111/j.1476-5381.2011.01566.x. Br J Pharmacol. 2012. PMID: 21718305 Free PMC article.
The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor-β and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist.
Cipriani P, Di Benedetto P, Ruscitti P, Capece D, Zazzeroni F, Liakouli V, Pantano I, Berardicurti O, Carubbi F, Pecetti G, Turricchia S, Alesse E, Iglarz M, Giacomelli R. Cipriani P, et al. Among authors: di benedetto p. J Rheumatol. 2015 Oct;42(10):1808-16. doi: 10.3899/jrheum.150088. Epub 2015 Aug 15. J Rheumatol. 2015. PMID: 26276964
Blocking Jak/STAT signalling using tofacitinib inhibits angiogenesis in experimental arthritis.
Di Benedetto P, Ruscitti P, Berardicurti O, Panzera N, Grazia N, Di Vito Nolfi M, Di Francesco B, Navarini L, Maurizi A, Rucci N, Teti AM, Zazzeroni F, Guggino G, Ciccia F, Dolo V, Alesse E, Cipriani P, Giacomelli R. Di Benedetto P, et al. Among authors: di francesco b, di vito nolfi m. Arthritis Res Ther. 2021 Aug 14;23(1):213. doi: 10.1186/s13075-021-02587-8. Arthritis Res Ther. 2021. PMID: 34391476 Free PMC article.
Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis.
Ciccia F, Guggino G, Rizzo A, Alessandro R, Luchetti MM, Milling S, Saieva L, Cypers H, Stampone T, Di Benedetto P, Gabrielli A, Fasano A, Elewaut D, Triolo G. Ciccia F, et al. Among authors: di benedetto p. Ann Rheum Dis. 2017 Jun;76(6):1123-1132. doi: 10.1136/annrheumdis-2016-210000. Epub 2017 Jan 9. Ann Rheum Dis. 2017. PMID: 28069576 Free PMC article.
H-ferritin and CD68(+) /H-ferritin(+) monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease.
Ruscitti P, Cipriani P, Ciccia F, Di Benedetto P, Liakouli V, Berardicurti O, Carubbi F, Guggino G, Di Bartolomeo S, Triolo G, Giacomelli R. Ruscitti P, et al. Among authors: di benedetto p, di bartolomeo s. Clin Exp Immunol. 2016 Oct;186(1):30-8. doi: 10.1111/cei.12826. Epub 2016 Jul 28. Clin Exp Immunol. 2016. PMID: 27317930 Free PMC article.
Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: a new potential target for antifibrotic therapy.
Di Benedetto P, Liakouli V, Ruscitti P, Berardicurti O, Carubbi F, Panzera N, Di Bartolomeo S, Guggino G, Ciccia F, Triolo G, Cipriani P, Giacomelli R. Di Benedetto P, et al. Among authors: di bartolomeo s. Arthritis Res Ther. 2018 Oct 3;20(1):223. doi: 10.1186/s13075-018-1719-4. Arthritis Res Ther. 2018. PMID: 30285896 Free PMC article.
185 results