Dhouib R - Search Results

1

Profluorescent Fluoroquinolone-Nitroxides for Investigating Antibiotic⁻Bacterial Interactions.

Verderosa AD, Dhouib R, Fairfull-Smith KE, Totsika M. Verderosa AD, et al. Among authors: dhouib r. Antibiotics (Basel). 2019 Mar 4;8(1):19. doi: 10.3390/antibiotics8010019. Antibiotics (Basel). 2019. PMID: 30836686 Free PMC article.

2

Eradicating uropathogenic Escherichia coli biofilms with a ciprofloxacin-dinitroxide conjugate.

Verderosa AD, Harris J, Dhouib R, Totsika M, Fairfull-Smith KE. Verderosa AD, et al. Among authors: dhouib r. Medchemcomm. 2019 Feb 25;10(5):699-711. doi: 10.1039/c9md00062c. eCollection 2019 May 1. Medchemcomm. 2019. PMID: 31191860 Free PMC article.

3

Nitroxide Functionalized Antibiotics Are Promising Eradication Agents against Staphylococcus aureus Biofilms.

Verderosa AD, Dhouib R, Fairfull-Smith KE, Totsika M. Verderosa AD, et al. Among authors: dhouib r. Antimicrob Agents Chemother. 2019 Dec 20;64(1):e01685-19. doi: 10.1128/AAC.01685-19. Print 2019 Dec 20. Antimicrob Agents Chemother. 2019. PMID: 31636066 Free PMC article.

4

A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics.

Verderosa AD, Dhouib R, Hong Y, Anderson TK, Heras B, Totsika M. Verderosa AD, et al. Among authors: dhouib r. Sci Rep. 2021 Jan 15;11(1):1569. doi: 10.1038/s41598-021-81007-y. Sci Rep. 2021. PMID: 33452354 Free PMC article.

5

An in vitro Reconstructed Human Skin Equivalent Model to Study the Role of Skin Integration Around Percutaneous Devices Against Bacterial Infection.

Bolle ECL, Verderosa AD, Dhouib R, Parker TJ, Fraser JF, Dargaville TR, Totsika M. Bolle ECL, et al. Among authors: dhouib r. Front Microbiol. 2020 May 14;11:670. doi: 10.3389/fmicb.2020.00670. eCollection 2020. Front Microbiol. 2020. PMID: 32477277 Free PMC article.

6

Antivirulence DsbA inhibitors attenuate Salmonella enterica serovar Typhimurium fitness without detectable resistance.

Dhouib R, Vagenas D, Hong Y, Verderosa AD, Martin JL, Heras B, Totsika M. Dhouib R, et al. FASEB Bioadv. 2021 Feb 10;3(4):231-242. doi: 10.1096/fba.2020-00100. eCollection 2021 Apr. FASEB Bioadv. 2021. PMID: 33842848 Free PMC article.

7

Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens.

Totsika M, Vagenas D, Paxman JJ, Wang G, Dhouib R, Sharma P, Martin JL, Scanlon MJ, Heras B. Totsika M, et al. Among authors: dhouib r. Antioxid Redox Signal. 2018 Sep 1;29(7):653-666. doi: 10.1089/ars.2017.7104. Epub 2018 Feb 1. Antioxid Redox Signal. 2018. PMID: 29237285 Free PMC article.

8

Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.

Duncan LF, Wang G, Ilyichova OV, Dhouib R, Totsika M, Scanlon MJ, Heras B, Abbott BM. Duncan LF, et al. Among authors: dhouib r. Bioorg Med Chem. 2021 Sep 1;45:116315. doi: 10.1016/j.bmc.2021.116315. Epub 2021 Jul 22. Bioorg Med Chem. 2021. PMID: 34364222

9

Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials.

Wang G, Mohanty B, Williams ML, Doak BC, Dhouib R, Totsika M, McMahon RM, Sharma G, Zheng D, Bentley MR, Ka-Yan Chin Y, Horne J, Chalmers DK, Heras B, Scanlon MJ. Wang G, et al. Among authors: dhouib r. ChemMedChem. 2022 Mar 18;17(6):e202100673. doi: 10.1002/cmdc.202100673. Epub 2022 Jan 27. ChemMedChem. 2022. PMID: 34978144 Free PMC article.

10

Control of Bacterial Sulfite Detoxification by Conserved and Species-Specific Regulatory Circuits.

Tan YJC, Zhao C, Nasreen M, O'Rourke L, Dhouib R, Roberts L, Wan Y, Beatson SA, Kappler U. Tan YJC, et al. Among authors: dhouib r. Front Microbiol. 2019 May 14;10:960. doi: 10.3389/fmicb.2019.00960. eCollection 2019. Front Microbiol. 2019. PMID: 31139157 Free PMC article.

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