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Immune-awakening revealed by peripheral T cell dynamics after one cycle of immunotherapy.
Valpione S, Galvani E, Tweedy J, Mundra PA, Banyard A, Middlehurst P, Barry J, Mills S, Salih Z, Weightman J, Gupta A, Gremel G, Baenke F, Dhomen N, Lorigan PC, Marais R. Valpione S, et al. Among authors: dhomen n. Nat Cancer. 2020 Feb;1(2):210-221. doi: 10.1038/s43018-019-0022-x. Epub 2020 Feb 10. Nat Cancer. 2020. PMID: 32110781 Free PMC article.
New insight into BRAF mutations in cancer.
Dhomen N, Marais R. Dhomen N, et al. Curr Opin Genet Dev. 2007 Feb;17(1):31-9. doi: 10.1016/j.gde.2006.12.005. Curr Opin Genet Dev. 2007. PMID: 17208430 Review.
Oncogenic Braf induces melanocyte senescence and melanoma in mice.
Dhomen N, Reis-Filho JS, da Rocha Dias S, Hayward R, Savage K, Delmas V, Larue L, Pritchard C, Marais R. Dhomen N, et al. Cancer Cell. 2009 Apr 7;15(4):294-303. doi: 10.1016/j.ccr.2009.02.022. Cancer Cell. 2009. PMID: 19345328 Free article.
BRAF signaling and targeted therapies in melanoma.
Dhomen N, Marais R. Dhomen N, et al. Hematol Oncol Clin North Am. 2009 Jun;23(3):529-45, ix. doi: 10.1016/j.hoc.2009.04.001. Hematol Oncol Clin North Am. 2009. PMID: 19464601 Review.
A mouse model of melanoma driven by oncogenic KRAS.
Milagre C, Dhomen N, Geyer FC, Hayward R, Lambros M, Reis-Filho JS, Marais R. Milagre C, et al. Among authors: dhomen n. Cancer Res. 2010 Jul 1;70(13):5549-57. doi: 10.1158/0008-5472.CAN-09-4254. Epub 2010 Jun 1. Cancer Res. 2010. PMID: 20516123 Free PMC article.
Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53.
Viros A, Sanchez-Laorden B, Pedersen M, Furney SJ, Rae J, Hogan K, Ejiama S, Girotti MR, Cook M, Dhomen N, Marais R. Viros A, et al. Among authors: dhomen n. Nature. 2014 Jul 24;511(7510):478-482. doi: 10.1038/nature13298. Epub 2014 Jun 11. Nature. 2014. PMID: 24919155 Free PMC article.
Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells.
Baenke F, Chaneton B, Smith M, Van Den Broek N, Hogan K, Tang H, Viros A, Martin M, Galbraith L, Girotti MR, Dhomen N, Gottlieb E, Marais R. Baenke F, et al. Among authors: dhomen n. Mol Oncol. 2016 Jan;10(1):73-84. doi: 10.1016/j.molonc.2015.08.003. Epub 2015 Aug 20. Mol Oncol. 2016. PMID: 26365896 Free PMC article.
Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma.
Girotti MR, Gremel G, Lee R, Galvani E, Rothwell D, Viros A, Mandal AK, Lim KH, Saturno G, Furney SJ, Baenke F, Pedersen M, Rogan J, Swan J, Smith M, Fusi A, Oudit D, Dhomen N, Brady G, Lorigan P, Dive C, Marais R. Girotti MR, et al. Among authors: dhomen n. Cancer Discov. 2016 Mar;6(3):286-99. doi: 10.1158/2159-8290.CD-15-1336. Epub 2015 Dec 29. Cancer Discov. 2016. PMID: 26715644
42 results