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Surveillance of SARS-CoV-2 variants of concern by identification of single nucleotide polymorphisms in the spike protein by a multiplex real-time PCR.
Gomes L, Jeewandara C, Jayadas TP, Dissanayake O, Harvie M, Guruge D, Withanage V, Mahesh PKB, Rajapakse W, Ramachandran R, Dharmarajan V, Pathiraja I, Sanjeewani A, Bandara P, Nanayakkara G, Francis VR, Kithsiri A, Edirisinghe DA, De Silva K, Wijayamuni R, Ogg GS, Waggoner J, Malavige GN. Gomes L, et al. Among authors: dharmarajan v. J Virol Methods. 2022 Feb;300:114374. doi: 10.1016/j.jviromet.2021.114374. Epub 2021 Nov 22. J Virol Methods. 2022. PMID: 34822912 Free PMC article.
HP1 reshapes nucleosome core to promote phase separation of heterochromatin.
Sanulli S, Trnka MJ, Dharmarajan V, Tibble RW, Pascal BD, Burlingame AL, Griffin PR, Gross JD, Narlikar GJ. Sanulli S, et al. Among authors: dharmarajan v. Nature. 2019 Nov;575(7782):390-394. doi: 10.1038/s41586-019-1669-2. Epub 2019 Oct 16. Nature. 2019. PMID: 31618757 Free PMC article.
Non-training clinical fellowships.
Fernando D, Dharmarajan V, Smith D, Cox G, Noor M, Haynes A. Fernando D, et al. Among authors: dharmarajan v. Future Healthc J. 2019 Jun;6(2):147-148. doi: 10.7861/futurehosp.6-2-147a. Future Healthc J. 2019. PMID: 31363526 Free PMC article. No abstract available.
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.
Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, Hosfield DJ, Chandarlapaty S, Tajkhorshid E, Nettles KW, Griffin PR, Shen Y, Katzenellenbogen JA, Brown M, Greene GL. Fanning SW, et al. Among authors: dharmarajan v. Elife. 2018 Nov 29;7:e37161. doi: 10.7554/eLife.37161. Elife. 2018. PMID: 30489256 Free PMC article.
Defining a Canonical Ligand-Binding Pocket in the Orphan Nuclear Receptor Nurr1.
de Vera IMS, Munoz-Tello P, Zheng J, Dharmarajan V, Marciano DP, Matta-Camacho E, Giri PK, Shang J, Hughes TS, Rance M, Griffin PR, Kojetin DJ. de Vera IMS, et al. Among authors: dharmarajan v. Structure. 2019 Jan 2;27(1):66-77.e5. doi: 10.1016/j.str.2018.10.002. Epub 2018 Nov 8. Structure. 2019. PMID: 30416039 Free PMC article.
Identification of potent RORβ modulators: Scaffold variation.
Doebelin C, Patouret R, Garcia-Ordonez RD, Chang MR, Dharmarajan V, Novick S, Ciesla A, Campbell S, Solt LA, Griffin PR, Kamenecka TM. Doebelin C, et al. Among authors: dharmarajan v. Bioorg Med Chem Lett. 2018 Oct 15;28(19):3210-3215. doi: 10.1016/j.bmcl.2018.08.017. Epub 2018 Aug 16. Bioorg Med Chem Lett. 2018. PMID: 30143422 Free PMC article.
Design, synthesis, and evaluation of simple phenol amides as ERRγ agonists.
Lin H, Doebelin C, Patouret R, Garcia-Ordonez RD, Chang MR, Dharmarajan V, Bayona CR, Cameron MD, Griffin PR, Kamenecka TM. Lin H, et al. Among authors: dharmarajan v. Bioorg Med Chem Lett. 2018 May 1;28(8):1313-1319. doi: 10.1016/j.bmcl.2018.03.019. Epub 2018 Mar 8. Bioorg Med Chem Lett. 2018. PMID: 29548571 Free PMC article.
57 results