Liposomal polyamine-dialkyl phosphate conjugates as effective gene carriers: chemical structure, morphology, and gene transfer activity.
Dewa T, Asai T, Tsunoda Y, Kato K, Baba D, Uchida M, Sumino A, Niwata K, Umemoto T, Iida K, Oku N, Nango M.
Dewa T, et al.
Bioconjug Chem. 2010 May 19;21(5):844-52. doi: 10.1021/bc900376y.
Bioconjug Chem. 2010.
PMID: 20377241
The conjugates were synthesized from dialkyl phosphates (with alkyl chain lengths of 12, 14, or 16 carbons) by reaction with the polyamine molecules, spermidine, spermine, or polyethylenimine (PEI(1800)). [Dewa, T., et al. Bioconjugate Chem. 2004, 15, 824]. The PCL …
The conjugates were synthesized from dialkyl phosphates (with alkyl chain lengths of 12, 14, or 16 carbons) by reaction with the polyamine m …