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Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody.
Baidya M, Chaturvedi M, Dwivedi-Agnihotri H, Ranjan A, Devost D, Namkung Y, Stepniewski TM, Pandey S, Baruah M, Panigrahi B, Sarma P, Yadav MK, Maharana J, Banerjee R, Kawakami K, Inoue A, Selent J, Laporte SA, Hébert TE, Shukla AK. Baidya M, et al. Among authors: devost d. Nat Commun. 2022 Aug 8;13(1):4634. doi: 10.1038/s41467-022-32386-x. Nat Commun. 2022. PMID: 35941121 Free PMC article.
A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway.
Goupil E, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, Laporte SA. Goupil E, et al. Among authors: devost d. J Biol Chem. 2010 Aug 13;285(33):25624-36. doi: 10.1074/jbc.M110.115196. Epub 2010 Jun 15. J Biol Chem. 2010. PMID: 20551320 Free PMC article.
Quantifying biased signaling in GPCRs using BRET-based biosensors.
Namkung Y, Radresa O, Armando S, Devost D, Beautrait A, Le Gouill C, Laporte SA. Namkung Y, et al. Among authors: devost d. Methods. 2016 Jan 1;92:5-10. doi: 10.1016/j.ymeth.2015.04.010. Epub 2015 Apr 15. Methods. 2016. PMID: 25890247
Dual allosteric modulation of opioid antinociceptive potency by α2A-adrenoceptors.
Chabot-Doré AJ, Millecamps M, Naso L, Devost D, Trieu P, Piltonen M, Diatchenko L, Fairbanks CA, Wilcox GL, Hébert TE, Stone LS. Chabot-Doré AJ, et al. Among authors: devost d. Neuropharmacology. 2015 Dec;99:285-300. doi: 10.1016/j.neuropharm.2015.08.010. Epub 2015 Aug 6. Neuropharmacology. 2015. PMID: 26254859 Free PMC article.
45 results