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Production in Bacteria and Characterization of Engineered Humanized Fab Fragment against the Nodal Protein.
Sivaccumar JP, Iaccarino E, Oliver A, Cantile M, Olimpieri P, Leonardi A, Ruvo M, Sandomenico A. Sivaccumar JP, et al. Pharmaceuticals (Basel). 2023 Aug 10;16(8):1130. doi: 10.3390/ph16081130. Pharmaceuticals (Basel). 2023. PMID: 37631045 Free PMC article.
Drug development in recent years is increasingly focused on developing personalized treatments based on blocking molecules selective for therapeutic targets specifically present in individual patients. ...Small antibody-like molecules, such as Fabs, are often …
Drug development in recent years is increasingly focused on developing personalized treatments based on blocking molecules sel …
Members of the GADD45 Protein Family Show Distinct Propensities to form Toxic Amyloid-Like Aggregates in Physiological Conditions.
Smaldone G, Caruso D, Sandomenico A, Iaccarino E, Focà A, Ruggiero A, Ruvo M, Vitagliano L. Smaldone G, et al. Int J Mol Sci. 2021 Oct 2;22(19):10700. doi: 10.3390/ijms221910700. Int J Mol Sci. 2021. PMID: 34639041 Free PMC article.
The three members (GADD45alpha, GADD45beta, and GADD45gamma) of the growth arrest and DNA damage-inducible 45 (GADD45) protein family are involved in a myriad of diversified cellular functions. ...
The three members (GADD45alpha, GADD45beta, and GADD45gamma) of the growth arrest and DNA damage-inducible 45 (GADD45) protein family …