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Novel non-HAP class A HBV capsid assembly modulators have distinct in vitro and in vivo profiles.
Vanrusselt H, Kum DB, Taverniti V, Liu C, Acosta Sanchez A, Corthout N, Munck S, Baumert TF, Beigelman L, Blatt LM, Symons JA, Deval J, Raboisson P, Verrier ER, Jekle A, Vendeville S, Debing Y. Vanrusselt H, et al. Among authors: deval j. J Virol. 2023 Oct 31;97(10):e0072223. doi: 10.1128/jvi.00722-23. Epub 2023 Sep 27. J Virol. 2023. PMID: 37754761 Free PMC article.
The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir.
Jochmans D, Liu C, Donckers K, Stoycheva A, Boland S, Stevens SK, De Vita C, Vanmechelen B, Maes P, Trüeb B, Ebert N, Thiel V, De Jonghe S, Vangeel L, Bardiot D, Jekle A, Blatt LM, Beigelman L, Symons JA, Raboisson P, Chaltin P, Marchand A, Neyts J, Deval J, Vandyck K. Jochmans D, et al. Among authors: deval j. mBio. 2023 Feb 28;14(1):e0281522. doi: 10.1128/mbio.02815-22. Epub 2023 Jan 10. mBio. 2023. PMID: 36625640 Free PMC article.
Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.
Kum DB, Vanrusselt H, Acosta Sanchez A, Taverniti V, Verrier ER, Baumert TF, Liu C, Deval J, Corthout N, Munck S, Beigelman L, Blatt LM, Symons JA, Raboisson P, Jekle A, Vendeville S, Debing Y. Kum DB, et al. Among authors: deval j. Hepatology. 2023 Oct 1;78(4):1252-1265. doi: 10.1097/HEP.0000000000000428. Epub 2023 Apr 28. Hepatology. 2023. PMID: 37102495
Tumor Regression upon Intratumoral and Subcutaneous Dosing of the STING Agonist ALG-031048 in Mouse Efficacy Models.
Jekle A, Thatikonda SK, Jaisinghani R, Ren S, Kinkade A, Stevens SK, Stoycheva A, Rajwanshi VK, Williams C, Deval J, Mukherjee S, Zhang Q, Chanda S, Smith DB, Blatt LM, Symons JA, Gonzalvez F, Beigelman L. Jekle A, et al. Among authors: deval j. Int J Mol Sci. 2023 Nov 13;24(22):16274. doi: 10.3390/ijms242216274. Int J Mol Sci. 2023. PMID: 38003463 Free PMC article.
Radiologic Features of Nodules Attached to the Mediastinal or Diaphragmatic Pleura at Low-Dose CT for Lung Cancer Screening.
Zhu Y, Yip R, Zhang J, Cai Q, Sun Q, Li P, Paksashvili N, Triphuridet N, Henschke CI, Yankelevitz DF; Investigators of the International Early Lung Cancer Action Program and Initiative for Early Lung Cancer Research on Treatment–Mount Sinai Health System; Investigators of the International Early Lung Cancer Action Program; Investigators of the Initiative for Early Lung Cancer Research on Treatment–Mount Sinai Health System. Zhu Y, et al. Radiology. 2024 Jan;310(1):e231219. doi: 10.1148/radiol.231219. Radiology. 2024. PMID: 38165250
Prospective Cohort Study to Compare Long-Term Lung Cancer-Specific and All-Cause Survival of Clinical Early Stage (T1a-b; ≤20 mm) NSCLC Treated by Stereotactic Body Radiation Therapy and Surgery.
Henschke CI, Yip R, Sun Q, Li P, Kaufman A, Samstein R, Connery C, Kohman L, Lee P, Tannous H, Yankelevitz DF, Taioli E, Rosenzweig K, Flores RM; I-ELCAP; IELCART Investigators. Henschke CI, et al. J Thorac Oncol. 2024 Mar;19(3):476-490. doi: 10.1016/j.jtho.2023.10.002. Epub 2023 Oct 6. J Thorac Oncol. 2024. PMID: 37806384
Meeting report: 34th international conference on antiviral research.
Brancale A, Carter K, Delang L, Deval J, Durantel D, Gentry BG, Jordan R, Julander JG, Lo MK, Pérez-Pérez MJ, Schang LM, Seley-Radtke KL, Shi PY, Vasudevan SG, Whitley RJ, Spengler JR. Brancale A, et al. Among authors: deval j. Antivir Chem Chemother. 2022 Jan-Dec;30:20402066221130853. doi: 10.1177/20402066221130853. Antivir Chem Chemother. 2022. PMID: 36305015 Free PMC article.
New or enlarging hiatal hernias after thoracic surgery for early lung cancer.
Song KJ, Yip R, Chung M, Cai Q, Zhu Y, Singh A, Lewis EE, Yankelevitz D, Taioli E, Henschke C, Flores R; Initiative for Early Lung Cancer Research on Treatment and International Early Lung Cancer Action Program Investigators. Song KJ, et al. JTCVS Open. 2022 Feb 23;10:415-423. doi: 10.1016/j.xjon.2022.02.013. eCollection 2022 Jun. JTCVS Open. 2022. PMID: 36004265 Free PMC article.
78 results