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Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal.
Ferreccio A, Mathieu J, Detraux D, Somasundaram L, Cavanaugh C, Sopher B, Fischer K, Bello T, M Hussein A, Levy S, Cook S, Sidhu SB, Artoni F, Palpant NJ, Reinecke H, Wang Y, Paddison P, Murry C, Jayadev S, Ware C, Ruohola-Baker H. Ferreccio A, et al. Among authors: detraux d. Cell Cycle. 2018;17(5):535-549. doi: 10.1080/15384101.2018.1442621. Epub 2018 Apr 5. Cell Cycle. 2018. PMID: 29466914 Free PMC article.
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H. Sperber H, et al. Among authors: detraux d. Nat Cell Biol. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16. Nat Cell Biol. 2015. PMID: 26571212 Free PMC article.
First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.
Moody JD, Levy S, Mathieu J, Xing Y, Kim W, Dong C, Tempel W, Robitaille AM, Dang LT, Ferreccio A, Detraux D, Sidhu S, Zhu L, Carter L, Xu C, Valensisi C, Wang Y, Hawkins RD, Min J, Moon RT, Orkin SH, Baker D, Ruohola-Baker H. Moody JD, et al. Among authors: detraux d. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10125-10130. doi: 10.1073/pnas.1706907114. Epub 2017 Sep 1. Proc Natl Acad Sci U S A. 2017. PMID: 28864533 Free PMC article.
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency.
Mathieu J, Detraux D, Kuppers D, Wang Y, Cavanaugh C, Sidhu S, Levy S, Robitaille AM, Ferreccio A, Bottorff T, McAlister A, Somasundaram L, Artoni F, Battle S, Hawkins RD, Moon RT, Ware CB, Paddison PJ, Ruohola-Baker H. Mathieu J, et al. Among authors: detraux d. Nat Commun. 2019 Feb 7;10(1):632. doi: 10.1038/s41467-018-08020-0. Nat Commun. 2019. PMID: 30733432 Free PMC article.
Metabolism as an early predictor of DPSCs aging.
Macrin D, Alghadeer A, Zhao YT, Miklas JW, Hussein AM, Detraux D, Robitaille AM, Madan A, Moon RT, Wang Y, Devi A, Mathieu J, Ruohola-Baker H. Macrin D, et al. Among authors: detraux d. Sci Rep. 2019 Feb 18;9(1):2195. doi: 10.1038/s41598-018-37489-4. Sci Rep. 2019. PMID: 30778087 Free PMC article.
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes.
Miklas JW, Clark E, Levy S, Detraux D, Leonard A, Beussman K, Showalter MR, Smith AT, Hofsteen P, Yang X, Macadangdang J, Manninen T, Raftery D, Madan A, Suomalainen A, Kim DH, Murry CE, Fiehn O, Sniadecki NJ, Wang Y, Ruohola-Baker H. Miklas JW, et al. Among authors: detraux d. Nat Commun. 2019 Oct 11;10(1):4671. doi: 10.1038/s41467-019-12482-1. Nat Commun. 2019. PMID: 31604922 Free PMC article.
microRNAs Regulating Human and Mouse Naïve Pluripotency.
Wang Y, Hussein AM, Somasundaram L, Sankar R, Detraux D, Mathieu J, Ruohola-Baker H. Wang Y, et al. Among authors: detraux d. Int J Mol Sci. 2019 Nov 22;20(23):5864. doi: 10.3390/ijms20235864. Int J Mol Sci. 2019. PMID: 31766734 Free PMC article.
Author Correction: TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes.
Miklas JW, Clark E, Levy S, Detraux D, Leonard A, Beussman K, Showalter MR, Smith AT, Hofsteen P, Yang X, Macadangdang J, Manninen T, Raftery D, Madan A, Suomalainen A, Kim DH, Murry CE, Fiehn O, Sniadecki NJ, Wang Y, Ruohola-Baker H. Miklas JW, et al. Among authors: detraux d. Nat Commun. 2020 May 8;11(1):2387. doi: 10.1038/s41467-020-16186-9. Nat Commun. 2020. PMID: 32385292 Free PMC article.
12 results