Desta Z - Search Results

1

Effects of SLCO1B1 polymorphisms on plasma estrogen concentrations in women with breast cancer receiving aromatase inhibitors exemestane and letrozole.

Dempsey JM, Kidwell KM, Gersch CL, Pesch AM, Desta Z, Storniolo AM, Stearns V, Skaar TC, Hayes DF, Henry NL, Rae JM, Hertz DL. Dempsey JM, et al. Among authors: desta z. Pharmacogenomics. 2019 Jun;20(8):571-580. doi: 10.2217/pgs-2019-0020. Pharmacogenomics. 2019. PMID: 31190621 Free PMC article. Clinical Trial.

2

Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism.

Rae JM, Soukhova NV, Flockhart DA, Desta Z. Rae JM, et al. Among authors: desta z. Drug Metab Dispos. 2002 May;30(5):525-30. doi: 10.1124/dmd.30.5.525. Drug Metab Dispos. 2002. PMID: 11950782

3

Sequence diversity and functional characterization of the 5'-regulatory region of human CYP2C19.

Arefayene M, Skaar TC, Zhao X, Rae JM, Tanus-Santos JE, Brinkmann U, Brehm I, Salat U, Nguyen A, Desta Z, Flockhart DA. Arefayene M, et al. Among authors: desta z. Pharmacogenetics. 2003 Apr;13(4):199-206. doi: 10.1097/00008571-200304000-00004. Pharmacogenetics. 2003. PMID: 12668916

4

Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine.

Stearns V, Johnson MD, Rae JM, Morocho A, Novielli A, Bhargava P, Hayes DF, Desta Z, Flockhart DA. Stearns V, et al. Among authors: desta z. J Natl Cancer Inst. 2003 Dec 3;95(23):1758-64. doi: 10.1093/jnci/djg108. J Natl Cancer Inst. 2003. PMID: 14652237 Clinical Trial.

5

CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment.

Jin Y, Desta Z, Stearns V, Ward B, Ho H, Lee KH, Skaar T, Storniolo AM, Li L, Araba A, Blanchard R, Nguyen A, Ullmer L, Hayden J, Lemler S, Weinshilboum RM, Rae JM, Hayes DF, Flockhart DA. Jin Y, et al. Among authors: desta z. J Natl Cancer Inst. 2005 Jan 5;97(1):30-9. doi: 10.1093/jnci/dji005. J Natl Cancer Inst. 2005. PMID: 15632378

6

Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen.

Lim YC, Desta Z, Flockhart DA, Skaar TC. Lim YC, et al. Among authors: desta z. Cancer Chemother Pharmacol. 2005 May;55(5):471-8. doi: 10.1007/s00280-004-0926-7. Epub 2005 Feb 1. Cancer Chemother Pharmacol. 2005. PMID: 15685451

7

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes.

Goetz MP, Rae JM, Suman VJ, Safgren SL, Ames MM, Visscher DW, Reynolds C, Couch FJ, Lingle WL, Flockhart DA, Desta Z, Perez EA, Ingle JN. Goetz MP, et al. Among authors: desta z. J Clin Oncol. 2005 Dec 20;23(36):9312-8. doi: 10.1200/JCO.2005.03.3266. J Clin Oncol. 2005. PMID: 16361630

8

Endoxifen, a secondary metabolite of tamoxifen, and 4-OH-tamoxifen induce similar changes in global gene expression patterns in MCF-7 breast cancer cells.

Lim YC, Li L, Desta Z, Zhao Q, Rae JM, Flockhart DA, Skaar TC. Lim YC, et al. Among authors: desta z. J Pharmacol Exp Ther. 2006 Aug;318(2):503-12. doi: 10.1124/jpet.105.100511. Epub 2006 May 11. J Pharmacol Exp Ther. 2006. PMID: 16690721

9

Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment.

Borges S, Desta Z, Li L, Skaar TC, Ward BA, Nguyen A, Jin Y, Storniolo AM, Nikoloff DM, Wu L, Hillman G, Hayes DF, Stearns V, Flockhart DA. Borges S, et al. Among authors: desta z. Clin Pharmacol Ther. 2006 Jul;80(1):61-74. doi: 10.1016/j.clpt.2006.03.013. Clin Pharmacol Ther. 2006. PMID: 16815318 Free article.

10

The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen.

Goetz MP, Knox SK, Suman VJ, Rae JM, Safgren SL, Ames MM, Visscher DW, Reynolds C, Couch FJ, Lingle WL, Weinshilboum RM, Fritcher EG, Nibbe AM, Desta Z, Nguyen A, Flockhart DA, Perez EA, Ingle JN. Goetz MP, et al. Among authors: desta z. Breast Cancer Res Treat. 2007 Jan;101(1):113-21. doi: 10.1007/s10549-006-9428-0. Epub 2006 Nov 18. Breast Cancer Res Treat. 2007. PMID: 17115111

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