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Tumor-associated lymphocytes (TAL) are competent to produce higher levels of cytokines in neoplastic pleural and peritoneal effusions than those found in sera and are able to release into culture higher levels of IL-2 and IL-6 than those released by PBMC.
Mantovani G, Macciò A, Versace R, Pisano M, Lai P, Esu S, Ghiani M, Dessì D, Turnu E, Santona MC, et al. Mantovani G, et al. Among authors: dessi d. J Mol Med (Berl). 1995 Aug;73(8):409-16. doi: 10.1007/BF00240140. J Mol Med (Berl). 1995. PMID: 8528743
Neo-adjuvant chemo-(immuno-)therapy of advanced squamous-cell head and neck carcinoma: a multicenter, phase III, randomized study comparing cisplatin + 5-fluorouracil (5-FU) with cisplatin + 5-FU + recombinant interleukin 2.
Mantovani G, Gebbia V, Airoldi M, Bumma C, Contu P, Bianchi A, Ghiani M, Dessì D, Massa E, Curreli L, Lampis B, Lai P, Mulas C, Testa A, Proto E, Cadeddu G, Tore G. Mantovani G, et al. Among authors: dessi d. Cancer Immunol Immunother. 1998 Nov;47(3):149-56. doi: 10.1007/s002620050515. Cancer Immunol Immunother. 1998. PMID: 9829840 Free PMC article. Clinical Trial.
Tumor-associated lympho-monocytes from neoplastic effusions are immunologically defective in comparison with patient autologous PBMCs but are capable of releasing high amounts of various cytokines.
Mantovani G, Macciò A, Pisano M, Versace R, Lai P, Esu S, Massa E, Ghiani M, Dessì D, Melis GB, Del Giacco GS. Mantovani G, et al. Among authors: dessi d. Int J Cancer. 1997 May 29;71(5):724-31. doi: 10.1002/(sici)1097-0215(19970529)71:5<724::aid-ijc6>3.0.co;2-t. Int J Cancer. 1997. PMID: 9180137 Free article.
Clinical evaluation of two dosages and schedules of ifosfamide in combination with cisplatin in neo-adjuvant chemotherapy of patients with advanced (stage III-IV) head and neck squamous cell carcinoma: a phase II randomized study.
Mantovani G, Ghiani M, Lai P, Maccio A, Dessi D, Succu G, Massa D, Curreli L, Mulas C, Esu S, Proto E, Cadeddu G, Tore G. Mantovani G, et al. Among authors: dessi d. Oncol Rep. 1998 Nov-Dec;5(6):1499-505. doi: 10.3892/or.5.6.1499. Oncol Rep. 1998. PMID: 9769395 Clinical Trial.
51 results