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A single short reprogramming early in life initiates and propagates an epigenetically related mechanism improving fitness and promoting an increased healthy lifespan.
Alle Q, Le Borgne E, Bensadoun P, Lemey C, Béchir N, Gabanou M, Estermann F, Bertrand-Gaday C, Pessemesse L, Toupet K, Desprat R, Vialaret J, Hirtz C, Noël D, Jorgensen C, Casas F, Milhavet O, Lemaitre JM. Alle Q, et al. Among authors: desprat r. Aging Cell. 2022 Nov;21(11):e13714. doi: 10.1111/acel.13714. Epub 2022 Oct 17. Aging Cell. 2022. PMID: 36251933 Free PMC article.
Best practices for mapping replication origins in eukaryotic chromosomes.
Besnard E, Desprat R, Ryan M, Kahli M, Aladjem MI, Lemaitre JM. Besnard E, et al. Among authors: desprat r. Curr Protoc Cell Biol. 2014 Sep 2;64:22.18.1-13. doi: 10.1002/0471143030.cb2218s64. Curr Protoc Cell Biol. 2014. PMID: 25181303 Free PMC article. Review.
DNA replication timing alterations identify common markers between distinct progeroid diseases.
Rivera-Mulia JC, Desprat R, Trevilla-Garcia C, Cornacchia D, Schwerer H, Sasaki T, Sima J, Fells T, Studer L, Lemaitre JM, Gilbert DM. Rivera-Mulia JC, et al. Among authors: desprat r. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10972-E10980. doi: 10.1073/pnas.1711613114. Epub 2017 Dec 1. Proc Natl Acad Sci U S A. 2017. PMID: 29196523 Free PMC article.
Generation of three Duchenne Muscular Dystrophy patient-specific induced pluripotent stem cell lines DMD_YoTaz_PhyMedEXp, DMD_RaPer_PhyMedEXp, DMD_OuMen_PhyMedEXp (INSRMi008-A, INSRMi009-A and INSRMi010-A).
Souidi M, Amédro P, Meyer P, Desprat R, Lemaître JM, Rivier F, Lacampagne A, Meli AC. Souidi M, et al. Among authors: desprat r. Stem Cell Res. 2020 Dec;49:102094. doi: 10.1016/j.scr.2020.102094. Epub 2020 Nov 19. Stem Cell Res. 2020. PMID: 33246213 Free article.
22 results