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Cholecystokinin attenuates β-cell apoptosis in both mouse and human islets.
Kim HT, Desouza AH, Umhoefer H, Han J, Anzia L, Sacotte SJ, Williams RA, Blumer JT, Bartosiak JT, Fontaine DA, Baan M, Kibbe CR, Davis DB. Kim HT, et al. Among authors: desouza ah. Transl Res. 2022 May;243:1-13. doi: 10.1016/j.trsl.2021.10.005. Epub 2021 Nov 3. Transl Res. 2022. PMID: 34740874 Free PMC article.
Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway.
Lewandowski SL, Cardone RL, Foster HR, Ho T, Potapenko E, Poudel C, VanDeusen HR, Sdao SM, Alves TC, Zhao X, Capozzi ME, de Souza AH, Jahan I, Thomas CJ, Nunemaker CS, Davis DB, Campbell JE, Kibbey RG, Merrins MJ. Lewandowski SL, et al. Cell Metab. 2020 Nov 3;32(5):736-750.e5. doi: 10.1016/j.cmet.2020.10.007. Cell Metab. 2020. PMID: 33147484 Free PMC article.
Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped.
Tariq M, de Souza AH, Bensellam M, Chae H, Jaffredo M, Close AF, Deglasse JP, Santos LRB, Buemi A, Mourad NI, Wojtusciszyn A, Raoux M, Gilon P, Broca C, Jonas JC. Tariq M, et al. Diabetologia. 2023 Apr;66(4):709-723. doi: 10.1007/s00125-022-05842-y. Epub 2022 Dec 2. Diabetologia. 2023. PMID: 36459178