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Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.
Meng W, Ellsworth BA, Nirschl AA, McCann PJ, Patel M, Girotra RN, Wu G, Sher PM, Morrison EP, Biller SA, Zahler R, Deshpande PP, Pullockaran A, Hagan DL, Morgan N, Taylor JR, Obermeier MT, Humphreys WG, Khanna A, Discenza L, Robertson JG, Wang A, Han S, Wetterau JR, Janovitz EB, Flint OP, Whaley JM, Washburn WN. Meng W, et al. Among authors: deshpande pp. J Med Chem. 2008 Mar 13;51(5):1145-9. doi: 10.1021/jm701272q. Epub 2008 Feb 9. J Med Chem. 2008. PMID: 18260618
A Claisen approach to 4'-Ed4T.
Gallagher WP, Deshpande PP, Li J, Katipally K, Sausker J. Gallagher WP, et al. Among authors: deshpande pp. Org Lett. 2015 Jan 2;17(1):14-7. doi: 10.1021/ol503095v. Epub 2014 Dec 18. Org Lett. 2015. PMID: 25522212
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