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Roux-en-Y gastric bypass induces hepatic transcriptomic signatures and plasma metabolite changes indicative of improved cholesterol homeostasis.
Lalloyer F, Mogilenko DA, Verrijken A, Haas JT, Lamazière A, Kouach M, Descat A, Caron S, Vallez E, Derudas B, Gheeraert C, Baugé E, Despres G, Dirinck E, Tailleux A, Dombrowicz D, Van Gaal L, Eeckhoute J, Lefebvre P, Goossens JF, Francque S, Staels B. Lalloyer F, et al. Among authors: descat a. J Hepatol. 2023 Oct;79(4):898-909. doi: 10.1016/j.jhep.2023.05.012. Epub 2023 May 23. J Hepatol. 2023. PMID: 37230231
Influence of Roux-en-Y gastric bypass on plasma bile acid profiles: a comparative study between rats, pigs and humans.
Spinelli V, Lalloyer F, Baud G, Osto E, Kouach M, Daoudi M, Vallez E, Raverdy V, Goossens JF, Descat A, Doytcheva P, Hubert T, Lutz TA, Lestavel S, Staels B, Pattou F, Tailleux A. Spinelli V, et al. Among authors: descat a. Int J Obes (Lond). 2016 Aug;40(8):1260-7. doi: 10.1038/ijo.2016.46. Epub 2016 Mar 22. Int J Obes (Lond). 2016. PMID: 27089995
NASH-related increases in plasma bile acid levels depend on insulin resistance.
Grzych G, Chávez-Talavera O, Descat A, Thuillier D, Verrijken A, Kouach M, Legry V, Verkindt H, Raverdy V, Legendre B, Caiazzo R, Van Gaal L, Goossens JF, Paumelle R, Francque S, Pattou F, Haas JT, Tailleux A, Staels B. Grzych G, et al. Among authors: descat a. JHEP Rep. 2020 Dec 16;3(2):100222. doi: 10.1016/j.jhepr.2020.100222. eCollection 2021 Apr. JHEP Rep. 2020. PMID: 33615207 Free PMC article.
Bile acids associate with glucose metabolism, but do not predict conversion from impaired fasting glucose to diabetes.
Chávez-Talavera O, Wargny M, Pichelin M, Descat A, Vallez E, Kouach M, Bigot-Corbel E, Joliveau M, Goossens JF, Le May C, Hadjadj S, Hanf R, Tailleux A, Staels B, Cariou B. Chávez-Talavera O, et al. Among authors: descat a. Metabolism. 2020 Feb;103:154042. doi: 10.1016/j.metabol.2019.154042. Epub 2019 Nov 27. Metabolism. 2020. PMID: 31785259
Characterization of one anastomosis gastric bypass and impact of biliary and common limbs on bile acid and postprandial glucose metabolism in a minipig model.
Marciniak C, Chávez-Talavera O, Caiazzo R, Hubert T, Zubiaga L, Baud G, Quenon A, Descat A, Vallez E, Goossens JF, Kouach M, Vangelder V, Gobert M, Daoudi M, Derudas B, Pigny P, Klein A, Gmyr V, Raverdy V, Lestavel S, Laferrère B, Staels B, Tailleux A, Pattou F. Marciniak C, et al. Among authors: descat a. Am J Physiol Endocrinol Metab. 2021 Apr 1;320(4):E772-E783. doi: 10.1152/ajpendo.00356.2020. Epub 2021 Jan 25. Am J Physiol Endocrinol Metab. 2021. PMID: 33491532 Free PMC article.
Plasma asymmetric dimethylarginine concentrations are not related to differences in maximal oxygen uptake in endurance trained and untrained men.
Pawlak-Chaouch M, Boissière J, Munyaneza D, Tagougui S, Gamelin FX, Cuvelier G, Heyman E, Goossens JF, Descat A, Berthoin S, Aucouturier J. Pawlak-Chaouch M, et al. Among authors: descat a. Exp Physiol. 2019 Feb;104(2):254-263. doi: 10.1113/EP087398. Epub 2018 Dec 18. Exp Physiol. 2019. PMID: 30561141 Free article.
Combined Metabolomics and Transcriptomics Approaches to Assess the IL-6 Blockade as a Therapeutic of ALS: Deleterious Alteration of Lipid Metabolism.
Patin F, Baranek T, Vourc'h P, Nadal-Desbarats L, Goossens JF, Marouillat S, Dessein AF, Descat A, Hounoum BM, Bruno C, Watier H, Si-Tahar M, Leman S, Lecron JC, Andres CR, Corcia P, Blasco H. Patin F, et al. Among authors: descat a. Neurotherapeutics. 2016 Oct;13(4):905-917. doi: 10.1007/s13311-016-0461-3. Neurotherapeutics. 2016. PMID: 27444617 Free PMC article.
18 results