Desai UR - Search Results

1

Structural Insights Into How Proteoglycans Determine Chemokine-CXCR1/CXCR2 Interactions: Progress and Challenges.

Rajarathnam K, Desai UR. Rajarathnam K, et al. Among authors: desai ur. Front Immunol. 2020 Apr 24;11:660. doi: 10.3389/fimmu.2020.00660. eCollection 2020. Front Immunol. 2020. PMID: 32391006 Free PMC article. Review.

2

Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions.

Joseph PR, Mosier PD, Desai UR, Rajarathnam K. Joseph PR, et al. Among authors: desai ur. Biochem J. 2015 Nov 15;472(1):121-33. doi: 10.1042/BJ20150059. Epub 2015 Sep 14. Biochem J. 2015. PMID: 26371375 Free PMC article.

3

Molecular Basis of Chemokine CXCL5-Glycosaminoglycan Interactions.

Sepuru KM, Nagarajan B, Desai UR, Rajarathnam K. Sepuru KM, et al. Among authors: desai ur. J Biol Chem. 2016 Sep 23;291(39):20539-50. doi: 10.1074/jbc.M116.745265. Epub 2016 Jul 28. J Biol Chem. 2016. PMID: 27471273 Free PMC article.

4

Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions.

Joseph PRB, Sawant KV, Iwahara J, Garofalo RP, Desai UR, Rajarathnam K. Joseph PRB, et al. Among authors: desai ur. Sci Rep. 2018 Aug 16;8(1):12289. doi: 10.1038/s41598-018-30697-y. Sci Rep. 2018. PMID: 30115951 Free PMC article.

5

Structural basis, stoichiometry, and thermodynamics of binding of the chemokines KC and MIP2 to the glycosaminoglycan heparin.

Sepuru KM, Nagarajan B, Desai UR, Rajarathnam K. Sepuru KM, et al. Among authors: desai ur. J Biol Chem. 2018 Nov 16;293(46):17817-17828. doi: 10.1074/jbc.RA118.004866. Epub 2018 Sep 26. J Biol Chem. 2018. PMID: 30257866 Free PMC article.

6

Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains.

Monneau YR, Luo L, Sankaranarayanan NV, Nagarajan B, Vivès RR, Baleux F, Desai UR, Arenzana-Seidedos F, Lortat-Jacob H. Monneau YR, et al. Among authors: desai ur. Open Biol. 2017 Oct;7(10):170133. doi: 10.1098/rsob.170133. Open Biol. 2017. PMID: 29070611 Free PMC article.

7

So you think computational approaches to understanding glycosaminoglycan-protein interactions are too dry and too rigid? Think again!

Sankaranarayanan NV, Nagarajan B, Desai UR. Sankaranarayanan NV, et al. Among authors: desai ur. Curr Opin Struct Biol. 2018 Jun;50:91-100. doi: 10.1016/j.sbi.2017.12.004. Epub 2018 Jan 9. Curr Opin Struct Biol. 2018. PMID: 29328962 Free PMC article. Review.

8

Sulfotransferase and Heparanase: Remodeling Engines in Promoting Virus Infection and Disease Development.

Kaltenbach DD, Jaishankar D, Hao M, Beer JC, Volin MV, Desai UR, Tiwari V. Kaltenbach DD, et al. Among authors: desai ur. Front Pharmacol. 2018 Nov 22;9:1315. doi: 10.3389/fphar.2018.01315. eCollection 2018. Front Pharmacol. 2018. PMID: 30555321 Free PMC article. Review.

9

A Synthetic, Small, Sulfated Agent Is a Promising Inhibitor of Chlamydia spp. Infection in vivo.

Gallegos KM, Taylor CR, Rabulinski DJ, Del Toro R, Girgis DE, Jourha D, Tiwari V, Desai UR, Ramsey KH. Gallegos KM, et al. Among authors: desai ur. Front Microbiol. 2019 Jan 16;9:3269. doi: 10.3389/fmicb.2018.03269. eCollection 2018. Front Microbiol. 2019. PMID: 30700982 Free PMC article.

10

Interaction of thrombin with sucrose octasulfate.

Desai BJ, Boothello RS, Mehta AY, Scarsdale JN, Wright HT, Desai UR. Desai BJ, et al. Among authors: desai ur. Biochemistry. 2011 Aug 16;50(32):6973-82. doi: 10.1021/bi2004526. Epub 2011 Jul 18. Biochemistry. 2011. PMID: 21736375 Free PMC article.

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