Desai A - Search Results

1

Lipid-peptide nanocomplexes for mRNA delivery in vitro and in vivo.

Grant-Serroukh D, Hunter MR, Maeshima R, Tagalakis AD, Aldossary AM, Allahham N, Williams GR, Edbrooke M, Desai A, Hart SL. Grant-Serroukh D, et al. Among authors: desai a. J Control Release. 2022 Aug;348:786-797. doi: 10.1016/j.jconrel.2022.06.018. Epub 2022 Jun 26. J Control Release. 2022. PMID: 35718210 Free article.

2

Using macropinocytosis for intracellular delivery of therapeutic nucleic acids to tumour cells.

Desai AS, Hunter MR, Kapustin AN. Desai AS, et al. Philos Trans R Soc Lond B Biol Sci. 2019 Feb 4;374(1765):20180156. doi: 10.1098/rstb.2018.0156. Philos Trans R Soc Lond B Biol Sci. 2019. PMID: 30967005 Free PMC article. Review.

3

Arrayed CRISPR Screening Identifies Novel Targets That Enhance the Productive Delivery of mRNA by MC3-Based Lipid Nanoparticles.

Ross-Thriepland D, Bornot A, Butler L, Desai A, Jaiswal H, Peel S, Hunter MR, Odunze U, Isherwood B, Gianni D. Ross-Thriepland D, et al. Among authors: desai a. SLAS Discov. 2020 Jul;25(6):605-617. doi: 10.1177/2472555220925770. Epub 2020 May 22. SLAS Discov. 2020. PMID: 32441189 Free PMC article.

4

Mechanistic Studies of an Automated Lipid Nanoparticle Reveal Critical Pharmaceutical Properties Associated with Enhanced mRNA Functional Delivery In Vitro and In Vivo.

Cui L, Hunter MR, Sonzini S, Pereira S, Romanelli SM, Liu K, Li W, Liang L, Yang B, Mahmoudi N, Desai AS. Cui L, et al. Small. 2022 Mar;18(9):e2105832. doi: 10.1002/smll.202105832. Epub 2021 Dec 16. Small. 2022. PMID: 34914866

5

Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles.

Hunter MR, Cui L, Porebski BT, Pereira S, Sonzini S, Odunze U, Iyer P, Engkvist O, Lloyd RL, Peel S, Sabirsh A, Ross-Thriepland D, Jones AT, Desai AS. Hunter MR, et al. Among authors: desai as. Small Methods. 2023 Sep;7(9):e2201695. doi: 10.1002/smtd.202201695. Epub 2023 Jun 14. Small Methods. 2023. PMID: 37317010 Free PMC article.

6

Endocytic Profiling of Cancer Cell Models Reveals Critical Factors Influencing LNP-Mediated mRNA Delivery and Protein Expression.

Sayers EJ, Peel SE, Schantz A, England RM, Beano M, Bates SM, Desai AS, Puri S, Ashford MB, Jones AT. Sayers EJ, et al. Among authors: desai as. Mol Ther. 2019 Nov 6;27(11):1950-1962. doi: 10.1016/j.ymthe.2019.07.018. Epub 2019 Aug 5. Mol Ther. 2019. PMID: 31427168 Free PMC article.

7

Development of a high-throughput platform for screening lipid nanoparticles for mRNA delivery.

Cui L, Pereira S, Sonzini S, van Pelt S, Romanelli SM, Liang L, Ulkoski D, Krishnamurthy VR, Brannigan E, Brankin C, Desai AS. Cui L, et al. Nanoscale. 2022 Jan 27;14(4):1480-1491. doi: 10.1039/d1nr06858j. Nanoscale. 2022. PMID: 35024714

8

Nanomedicines for the Delivery of Biologics.

Wahlich J, Desai A, Greco F, Hill K, Jones AT, Mrsny RJ, Pasut G, Perrie Y, Seib FP, Seymour LW, Uchegbu IF. Wahlich J, et al. Among authors: desai a. Pharmaceutics. 2019 May 3;11(5):210. doi: 10.3390/pharmaceutics11050210. Pharmaceutics. 2019. PMID: 31058802 Free PMC article.

9

A severe case of delayed transfusion reaction in a patient with sickle cell disease while preparing for allogeneic stem cell transplant.

Amit M, Barsotti K, Carll T, Desai AV, Kaviany S. Amit M, et al. Among authors: desai av. Pediatr Blood Cancer. 2024 May 16:e31086. doi: 10.1002/pbc.31086. Online ahead of print. Pediatr Blood Cancer. 2024. PMID: 38753388 No abstract available.

10

Effect of dapagliflozin in patients with diabetes and heart failure with mildly reduced or preserved ejection fraction according to background glucose-lowering therapy: A pre-specified analysis of the DELIVER trial.

Lassen MCH, Ostrominski JW, Inzucchi SE, Claggett BL, Kulac I, Jhund P, de Boer RA, Hernandez AF, Kosiborod MN, Lam CSP, Martinez FA, Shah SJ, Desai AS, Petersson M, Langkilde AM, Docherty KF, McMurray JJV, Solomon SD, Vaduganathan M. Lassen MCH, et al. Among authors: desai as. Eur J Heart Fail. 2024 May 15. doi: 10.1002/ejhf.3269. Online ahead of print. Eur J Heart Fail. 2024. PMID: 38745498

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