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The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis.
Nat Commun. 2021 Jun 29;12(1):4024. doi: 10.1038/s41467-021-24337-9.
Nat Commun. 2021.
PMID: 34188051
Free PMC article.
ExlA Pore-Forming Toxin: Localization at the Bacterial Membrane, Regulation of Secretion by Cyclic-Di-GMP, and Detection In Vivo.
Deruelle V, Berry A, Bouillot S, Job V, Maillard AP, Elsen S, Huber P.
Deruelle V, et al.
Toxins (Basel). 2021 Sep 11;13(9):645. doi: 10.3390/toxins13090645.
Toxins (Basel). 2021.
PMID: 34564649
Free PMC article.
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Inflammasome activation by Pseudomonas aeruginosa's ExlA pore-forming toxin is detrimental for the host.
Bouillot S, Pont S, Gallet B, Moriscot C, Deruelle V, Attrée I, Huber P.
Bouillot S, et al. Among authors: deruelle v.
Cell Microbiol. 2020 Nov;22(11):e13251. doi: 10.1111/cmi.13251. Epub 2020 Sep 6.
Cell Microbiol. 2020.
PMID: 32779854
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Bacterial Nucleotidyl Cyclases Activated by Calmodulin or Actin in Host Cells: Enzyme Specificities and Cytotoxicity Mechanisms Identified to Date.
Teixeira-Nunes M, Retailleau P, Comisso M, Deruelle V, Mechold U, Renault L.
Teixeira-Nunes M, et al. Among authors: deruelle v.
Int J Mol Sci. 2022 Jun 16;23(12):6743. doi: 10.3390/ijms23126743.
Int J Mol Sci. 2022.
PMID: 35743184
Free PMC article.
Review.
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Prevalence of ExoY Activity in Pseudomonas aeruginosa Reference Panel Strains and Impact on Cytotoxicity in Epithelial Cells.
Silistre H, Raoux-Barbot D, Mancinelli F, Sangouard F, Dupin A, Belyy A, Deruelle V, Renault L, Ladant D, Touqui L, Mechold U.
Silistre H, et al. Among authors: deruelle v.
Front Microbiol. 2021 Oct 4;12:666097. doi: 10.3389/fmicb.2021.666097. eCollection 2021.
Front Microbiol. 2021.
PMID: 34675890
Free PMC article.
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