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A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
Lee AW, Deruaz M, Lynch C, Davies G, Singh K, Alenazi Y, Eaton JRO, Kawamura A, Shaw J, Proudfoot AEI, Dias JM, Bhattacharya S. Lee AW, et al. Among authors: deruaz m. J Biol Chem. 2019 Jul 19;294(29):11199-11212. doi: 10.1074/jbc.RA119.008817. Epub 2019 Jun 5. J Biol Chem. 2019. PMID: 31167786 Free PMC article.
An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo.
Handel TM, Johnson Z, Rodrigues DH, Dos Santos AC, Cirillo R, Muzio V, Riva S, Mack M, Déruaz M, Borlat F, Vitte PA, Wells TN, Teixeira MM, Proudfoot AE. Handel TM, et al. Among authors: deruaz m. J Leukoc Biol. 2008 Oct;84(4):1101-8. doi: 10.1189/jlb.0108061. Epub 2008 Jul 28. J Leukoc Biol. 2008. PMID: 18662971 Free PMC article.
Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice.
Copin JC, da Silva RF, Fraga-Silva RA, Capettini L, Quintao S, Lenglet S, Pelli G, Galan K, Burger F, Braunersreuther V, Schaller K, Deruaz M, Proudfoot AE, Dallegri F, Stergiopulos N, Santos RA, Gasche Y, Mach F, Montecucco F. Copin JC, et al. Among authors: deruaz m. J Cereb Blood Flow Metab. 2013 Apr;33(4):490-8. doi: 10.1038/jcbfm.2012.198. Epub 2012 Dec 19. J Cereb Blood Flow Metab. 2013. PMID: 23250107 Free PMC article.
Treatment with a novel chemokine-binding protein or eosinophil lineage-ablation protects mice from experimental colitis.
Vieira AT, Fagundes CT, Alessandri AL, Castor MG, Guabiraba R, Borges VO, Silveira KD, Vieira EL, Gonçalves JL, Silva TA, Deruaz M, Proudfoot AE, Sousa LP, Teixeira MM. Vieira AT, et al. Among authors: deruaz m. Am J Pathol. 2009 Dec;175(6):2382-91. doi: 10.2353/ajpath.2009.090093. Epub 2009 Nov 5. Am J Pathol. 2009. PMID: 19893035 Free PMC article.
Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8+ T cells and limit CD4+ T-cell loss in BLT mice.
Calvet-Mirabent M, Claiborne DT, Deruaz M, Tanno S, Serra C, Delgado-Arévalo C, Sánchez-Cerrillo I, de Los Santos I, Sanz J, García-Fraile L, Sánchez-Madrid F, Alfranca A, Muñoz-Fernández MÁ, Allen TM, Buzón MJ, Balazs A, Vrbanac V, Martín-Gayo E. Calvet-Mirabent M, et al. Among authors: deruaz m. Eur J Immunol. 2022 Mar;52(3):447-461. doi: 10.1002/eji.202149502. Epub 2022 Jan 8. Eur J Immunol. 2022. PMID: 34935145 Free article.
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