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Anticancer properties of indole derivatives as IsoCombretastatin A-4 analogues.
Pecnard S, Hamze A, Bignon J, Prost B, Deroussent A, Gallego-Yerga L, Peláez R, Paik JY, Diederich M, Alami M, Provot O. Pecnard S, et al. Among authors: deroussent a. Eur J Med Chem. 2021 Nov 5;223:113656. doi: 10.1016/j.ejmech.2021.113656. Epub 2021 Jun 18. Eur J Med Chem. 2021. PMID: 34171660
1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.
Naret T, Khelifi I, Provot O, Bignon J, Levaique H, Dubois J, Souce M, Kasselouri A, Deroussent A, Paci A, Varela PF, Gigant B, Alami M, Hamze A. Naret T, et al. Among authors: deroussent a. J Med Chem. 2019 Feb 28;62(4):1902-1916. doi: 10.1021/acs.jmedchem.8b01386. Epub 2018 Dec 21. J Med Chem. 2019. PMID: 30525602
Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors.
Hauguel C, Ducellier S, Provot O, Ibrahim N, Lamaa D, Balcerowiak C, Letribot B, Nascimento M, Blanchard V, Askenatzis L, Levaique H, Bignon J, Baschieri F, Bauvais C, Bollot G, Renko D, Deroussent A, Prost B, Laisne MC, Michallet S, Lafanechère L, Papot S, Montagnac G, Tran C, Alami M, Apcher S, Hamze A. Hauguel C, et al. Among authors: deroussent a. Eur J Med Chem. 2022 Oct 5;240:114573. doi: 10.1016/j.ejmech.2022.114573. Epub 2022 Jul 1. Eur J Med Chem. 2022. PMID: 35797900 Free article.
Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.
Skarbek C, Lesueur LL, Chapuis H, Deroussent A, Pioche Durieu C, Daville A, Caron J, Rivard M, Martens T, Bertrand JR, Le Cam E, Vassal G, Couvreur P, Desmaele D, Paci A. Skarbek C, et al. Among authors: deroussent a. J Med Chem. 2015 Jan 22;58(2):705-17. doi: 10.1021/jm501224x. Epub 2014 Dec 23. J Med Chem. 2015. PMID: 25494842
Self-association and domains of interactions of an amphipathic helix peptide inhibitor of HIV-1 integrase assessed by analytical ultracentrifugation and NMR experiments in trifluoroethanol/H(2)O mixtures.
Maroun RG, Krebs D, El Antri S, Deroussent A, Lescot E, Troalen F, Porumb H, Goldberg ME, Fermandjian S. Maroun RG, et al. Among authors: deroussent a. J Biol Chem. 1999 Nov 26;274(48):34174-85. doi: 10.1074/jbc.274.48.34174. J Biol Chem. 1999. PMID: 10567389 Free article.
Simultaneous quantification of preactivated ifosfamide derivatives and of 4-hydroxyifosfamide by high performance liquid chromatography-tandem mass spectrometry in mouse plasma and its application to a pharmacokinetic study.
Deroussent A, Skarbek C, Maury A, Chapuis H, Daudigeos-Dubus E, Le Dret L, Durand S, Couvreur P, Desmaële D, Paci A. Deroussent A, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jun 15;992:30-5. doi: 10.1016/j.jchromb.2015.04.025. Epub 2015 Apr 20. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 25939095
40 results