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Anisaxins, helical antimicrobial peptides from marine parasites, kill resistant bacteria by lipid extraction and membrane disruption.
Rončević T, Gerdol M, Mardirossian M, Maleš M, Cvjetan S, Benincasa M, Maravić A, Gajski G, Krce L, Aviani I, Hrabar J, Trumbić Ž, Derks M, Pallavicini A, Weingarth M, Zoranić L, Tossi A, Mladineo I. Rončević T, et al. Among authors: derks m. Acta Biomater. 2022 Jul 1;146:131-144. doi: 10.1016/j.actbio.2022.04.025. Epub 2022 Apr 22. Acta Biomater. 2022. PMID: 35470073
Teixobactin kills bacteria by a two-pronged attack on the cell envelope.
Shukla R, Lavore F, Maity S, Derks MGN, Jones CR, Vermeulen BJA, Melcrová A, Morris MA, Becker LM, Wang X, Kumar R, Medeiros-Silva J, van Beekveld RAM, Bonvin AMJJ, Lorent JH, Lelli M, Nowick JS, MacGillavry HD, Peoples AJ, Spoering AL, Ling LL, Hughes DE, Roos WH, Breukink E, Lewis K, Weingarth M. Shukla R, et al. Among authors: derks mgn. Nature. 2022 Aug;608(7922):390-396. doi: 10.1038/s41586-022-05019-y. Epub 2022 Aug 3. Nature. 2022. PMID: 35922513 Free PMC article.
Specific Lipid Studies in Complex Membranes by Solid-State NMR Spectroscopy.
van Beekveld RAM, Derks MGN, Kumar R, Smid L, Maass T, Medeiros-Silva J, Breukink E, Weingarth M. van Beekveld RAM, et al. Among authors: derks mgn. Chemistry. 2022 Dec 15;28(70):e202202472. doi: 10.1002/chem.202202472. Epub 2022 Oct 25. Chemistry. 2022. PMID: 36098094 Free PMC article.
An antibiotic from an uncultured bacterium binds to an immutable target.
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, De Benedetti S, Krueger AM, Vermeulen BJA, Harbig T, Lavore F, Kumar R, Honorato RV, Grein F, Nieselt K, Liu Y, Bonvin AMJJ, Baldus M, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwalen CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, Weingarth M. Shukla R, et al. Among authors: derks mgn. Cell. 2023 Sep 14;186(19):4059-4073.e27. doi: 10.1016/j.cell.2023.07.038. Epub 2023 Aug 22. Cell. 2023. PMID: 37611581 Free article.
Toxicity in Older Patients with Cancer Receiving Immunotherapy: An Observational Study.
Tran Van Hoi E, Trompet S, Van Holstein Y, Van Den Bos F, Van Heemst D, Codrington H, Labots G, Lohman S, Ozkan A, Portielje J, Mooijaart SP, De Glas NA, Derks M. Tran Van Hoi E, et al. Among authors: derks m. Drugs Aging. 2024 May;41(5):431-441. doi: 10.1007/s40266-024-01114-z. Epub 2024 May 10. Drugs Aging. 2024. PMID: 38727992 Free PMC article.
161 results