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Tau in the gut, does it really matter?
Derkinderen P, Rolli-Derkinderen M, Chapelet G, Neunlist M, Noble W. Derkinderen P, et al. J Neurochem. 2021 Jul;158(2):94-104. doi: 10.1111/jnc.15320. Epub 2021 Feb 24. J Neurochem. 2021. PMID: 33569813 Free article. Review.
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.
Derkinderen P, Scales TM, Hanger DP, Leung KY, Byers HL, Ward MA, Lenz C, Price C, Bird IN, Perera T, Kellie S, Williamson R, Noble W, Van Etten RA, Leroy K, Brion JP, Reynolds CH, Anderton BH. Derkinderen P, et al. J Neurosci. 2005 Jul 13;25(28):6584-93. doi: 10.1523/JNEUROSCI.1487-05.2005. J Neurosci. 2005. PMID: 16014719 Free PMC article.
The microtubule-associated protein tau is also phosphorylated on tyrosine.
Lebouvier T, Scales TM, Williamson R, Noble W, Duyckaerts C, Hanger DP, Reynolds CH, Anderton BH, Derkinderen P. Lebouvier T, et al. Among authors: derkinderen p. J Alzheimers Dis. 2009;18(1):1-9. doi: 10.3233/JAD-2009-1116. J Alzheimers Dis. 2009. PMID: 19542604 Review.
The second brain and Parkinson's disease.
Lebouvier T, Chaumette T, Paillusson S, Duyckaerts C, Bruley des Varannes S, Neunlist M, Derkinderen P. Lebouvier T, et al. Among authors: derkinderen p. Eur J Neurosci. 2009 Sep;30(5):735-41. doi: 10.1111/j.1460-9568.2009.06873.x. Epub 2009 Aug 27. Eur J Neurosci. 2009. PMID: 19712093 Review.
Enteric glial cells protect neurons from oxidative stress in part via reduced glutathione.
Abdo H, Derkinderen P, Gomes P, Chevalier J, Aubert P, Masson D, Galmiche JP, Vanden Berghe P, Neunlist M, Lardeux B. Abdo H, et al. Among authors: derkinderen p. FASEB J. 2010 Apr;24(4):1082-94. doi: 10.1096/fj.09-139519. Epub 2009 Nov 11. FASEB J. 2010. PMID: 19906678
Our study identified the neuroprotective effects of EGCs via their release of reduced glutathione, extending their critical role in physiological contexts and in enteric neuropathies.-Abdo, H., Derkinderen, P., Gomes, P., Chevalier, J., Aubert, P., Mas …
Our study identified the neuroprotective effects of EGCs via their release of reduced glutathione, extending their critical role in physiolo …
α-Synuclein expression is induced by depolarization and cyclic AMP in enteric neurons.
Paillusson S, Tasselli M, Lebouvier T, Mahé MM, Chevalier J, Biraud M, Cario-Toumaniantz C, Neunlist M, Derkinderen P. Paillusson S, et al. Among authors: derkinderen p. J Neurochem. 2010 Nov;115(3):694-706. doi: 10.1111/j.1471-4159.2010.06962.x. Epub 2010 Sep 27. J Neurochem. 2010. PMID: 20731759 Free article.
Colonic biopsies to assess the neuropathology of Parkinson's disease and its relationship with symptoms.
Lebouvier T, Neunlist M, Bruley des Varannes S, Coron E, Drouard A, N'Guyen JM, Chaumette T, Tasselli M, Paillusson S, Flamand M, Galmiche JP, Damier P, Derkinderen P. Lebouvier T, et al. Among authors: derkinderen p. PLoS One. 2010 Sep 14;5(9):e12728. doi: 10.1371/journal.pone.0012728. PLoS One. 2010. PMID: 20856865 Free PMC article. Clinical Trial.
Biopsable neural tissues: toward new biomarkers for Parkinson's disease?
Lebouvier T, Tasselli M, Paillusson S, Pouclet H, Neunlist M, Derkinderen P. Lebouvier T, et al. Among authors: derkinderen p. Front Psychiatry. 2010 Sep 3;1:128. doi: 10.3389/fpsyt.2010.00128. eCollection 2010. Front Psychiatry. 2010. PMID: 21423439 Free PMC article.
191 results