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Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction.
Bageghni SA, Hemmings KE, Yuldasheva NY, Maqbool A, Gamboa-Esteves FO, Humphreys NE, Jackson MS, Denton CP, Francis S, Porter KE, Ainscough JF, Pinteaux E, Drinkhill MJ, Turner NA. Bageghni SA, et al. Among authors: denton cp. JCI Insight. 2019 Aug 8;5(17):e125074. doi: 10.1172/jci.insight.125074. JCI Insight. 2019. PMID: 31393855 Free PMC article.
An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor β receptor.
Hoyles RK, Derrett-Smith EC, Khan K, Shiwen X, Howat SL, Wells AU, Abraham DJ, Denton CP. Hoyles RK, et al. Among authors: denton cp. Am J Respir Crit Care Med. 2011 Jan 15;183(2):249-61. doi: 10.1164/rccm.201002-0279OC. Epub 2010 Aug 13. Am J Respir Crit Care Med. 2011. PMID: 20709822
Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice.
Denton CP, Zheng B, Evans LA, Shi-wen X, Ong VH, Fisher I, Lazaridis K, Abraham DJ, Black CM, de Crombrugghe B. Denton CP, et al. J Biol Chem. 2003 Jul 4;278(27):25109-19. doi: 10.1074/jbc.M300636200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707256 Free article.
Cytokines in the immunopathology of systemic sclerosis.
Raja J, Denton CP. Raja J, et al. Among authors: denton cp. Semin Immunopathol. 2015 Sep;37(5):543-57. doi: 10.1007/s00281-015-0511-7. Epub 2015 Jul 8. Semin Immunopathol. 2015. PMID: 26152640 Review.
Interleukin-31 promotes pathogenic mechanisms underlying skin and lung fibrosis in scleroderma.
Yaseen B, Lopez H, Taki Z, Zafar S, Rosario H, Abdi BA, Vigneswaran S, Xing F, Arumalla N, Black S, Ahmad S, Kumar K, Gul R, Scolamiero L, Morris S, Bowman A, Stainer A, Rice A, Stock C, Renzoni E, Denton CP, Venturini C, Brown M, O'Reilly S, Stratton R. Yaseen B, et al. Among authors: denton cp. Rheumatology (Oxford). 2020 Sep 1;59(9):2625-2636. doi: 10.1093/rheumatology/keaa195. Rheumatology (Oxford). 2020. PMID: 32365362
524 results