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Rationally designed immunogens enable immune focusing to the SARS-CoV-2 receptor binding motif.
bioRxiv [Preprint]. 2021 Jul 9:2021.03.15.435440. doi: 10.1101/2021.03.15.435440.
bioRxiv. 2021.
PMID: 33758851
Free PMC article.
Updated.
Preprint.
Engineered receptor binding domain immunogens elicit pan-sarbecovirus neutralizing antibodies outside the receptor binding motif.
Hauser BM, Sangesland M, Lam EC, Denis KJS, Feldman J, Yousif AS, Caradonna TM, Kannegieter T, Balazs AB, Lingwood D, Schmidt AG.
Hauser BM, et al. Among authors: denis kjs.
bioRxiv [Preprint]. 2021 Jun 29:2020.12.07.415216. doi: 10.1101/2020.12.07.415216.
bioRxiv. 2021.
PMID: 33330872
Free PMC article.
Preprint.
Item in Clipboard
T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all prior infected and vaccinated individuals.
Naranbhai V, Nathan A, Kaseke C, Berrios C, Khatri A, Choi S, Getz MA, Tano-Menka R, Ofoman O, Gayton A, Senjobe F, Denis KJS, Lam EC, Garcia-Beltran WF, Balazs AB, Walker BD, Iafrate AJ, Gaiha GD.
Naranbhai V, et al. Among authors: denis kjs.
medRxiv [Preprint]. 2022 Jan 5:2022.01.04.21268586. doi: 10.1101/2022.01.04.21268586.
medRxiv. 2022.
PMID: 35018386
Free PMC article.
Updated.
Preprint.
Item in Clipboard
Heterologous sarbecovirus receptor binding domains as scaffolds for SARS-CoV-2 receptor binding motif presentation.
Hauser BM, Sangesland M, Lam EC, Denis KJS, Sheehan ML, Vu ML, Cheng AH, Balazs AB, Lingwood D, Schmidt AG.
Hauser BM, et al. Among authors: denis kjs.
bioRxiv [Preprint]. 2023 Aug 22:2023.08.21.554179. doi: 10.1101/2023.08.21.554179.
bioRxiv. 2023.
PMID: 37662405
Free PMC article.
Updated.
Preprint.
Item in Clipboard
Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds.
Wamhoff EC, Ronsard L, Feldman J, Knappe GA, Hauser BM, Romanov A, Case JB, Sanapala S, Lam EC, Denis KJS, Boucau J, Barczak AK, Balazs AB, Diamond MS, Schmidt AG, Lingwood D, Bathe M.
Wamhoff EC, et al. Among authors: denis kjs.
Nat Commun. 2024 Jan 30;15(1):795. doi: 10.1038/s41467-024-44869-0.
Nat Commun. 2024.
PMID: 38291019
Free PMC article.
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