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Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode.
Hedir S, De Giorgi M, Fogha J, De Pascale M, Weiswald LB, Brotin E, Marekha B, Denoyelle C, Denis C, Suzanne P, Gautier F, Juin P, Ligat L, Lopez F, Carlier L, Legay R, Bureau R, Rault S, Poulain L, Oliveira Santos JS, Voisin-Chiret AS. Hedir S, et al. Among authors: denis c. Eur J Med Chem. 2018 Nov 5;159:357-380. doi: 10.1016/j.ejmech.2018.10.003. Epub 2018 Oct 4. Eur J Med Chem. 2018. PMID: 30308410
Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy.
Gozzi GJ, Gonzalez D, Boudesco C, Dias AMM, Gotthard G, Uyanik B, Dondaine L, Marcion G, Hermetet F, Denis C, Hardy L, Suzanne P, Douhard R, Jego G, Dubrez L, Demidov ON, Neiers F, Briand L, Sopková-de Oliveira Santos J, Voisin-Chiret AS, Garrido C. Gozzi GJ, et al. Among authors: denis c. Cell Death Differ. 2020 Jan;27(1):117-129. doi: 10.1038/s41418-019-0343-4. Epub 2019 May 8. Cell Death Differ. 2020. PMID: 31068676 Free PMC article.
Hot-Spots of Mcl-1 Protein.
Denis C, Sopková-de Oliveira Santos J, Bureau R, Voisin-Chiret AS. Denis C, et al. J Med Chem. 2020 Feb 13;63(3):928-943. doi: 10.1021/acs.jmedchem.9b00983. Epub 2019 Oct 16. J Med Chem. 2020. PMID: 31580668 Review.
Binding mode of Pyridoclax to myeloid cell leukemia-1 (Mcl-1) revealed by nuclear magnetic resonance spectroscopy, docking and molecular dynamics approaches.
Bourafai-Aziez A, Sebban M, Benabderrahmane M, Marekha B, Denis C, Paysant H, Weiswald LB, Carlier L, Bureau R, Coadou G, Ravault D, Voisin-Chiret AS, Sopková-de Oliveira Santos J, Oulyadi H. Bourafai-Aziez A, et al. Among authors: denis c. J Biomol Struct Dyn. 2020 Sep;38(14):4162-4178. doi: 10.1080/07391102.2019.1680434. Epub 2019 Oct 29. J Biomol Struct Dyn. 2020. PMID: 31612791
Fitusiran reduces bleeding in Factor X-deficient mice.
Verhenne S, McCluskey G, Maynadié H, Adam F, Casari C, Panicot-Dubois L, Crescence L, Dubois C, Denis CV, Lenting PJ, Christophe OD. Verhenne S, et al. Among authors: denis cv. Blood. 2024 Apr 15:blood.2023023404. doi: 10.1182/blood.2023023404. Online ahead of print. Blood. 2024. PMID: 38620079
Safety and Efficacy of Mini-invasive left atrial appendage closure : a propensity score analysis.
Denis C, Clerfond G, Chalard A, Riocreux C, Pereira B, Lamallem O, Guizani T, Catalan PA, Boudias A, Jean F, Bouchant-Pioche M, Abu-Alrub S, Combaret N, Souteyrand G, Motreff P, Jabaudon M, Futier E, Massoullie G, Eschalier R. Denis C, et al. Can J Cardiol. 2024 Apr 1:S0828-282X(24)00289-7. doi: 10.1016/j.cjca.2024.03.021. Online ahead of print. Can J Cardiol. 2024. PMID: 38570114
614 results