Dengl S - Search Results

1

Understanding the Half-Life Extension of Intravitreally Administered Antibodies Binding to Ocular Albumin.

Hauri S, Jakubiak P, Fueth M, Dengl S, Belli S, Alvarez-Sánchez R, Caruso A. Hauri S, et al. Among authors: dengl s. Pharmaceutics. 2020 Aug 26;12(9):810. doi: 10.3390/pharmaceutics12090810. Pharmaceutics. 2020. PMID: 32858986 Free PMC article.

2

PK modulation of haptenylated peptides via non-covalent antibody complexation.

Hoffmann E, Konkar A, Dziadek S, Josel HP, Conde-Knape K, Kropp H, Kling L, Stubenrauch K, Thorey I, Dengl S, Brinkmann U. Hoffmann E, et al. Among authors: dengl s. J Control Release. 2013 Oct 10;171(1):48-56. doi: 10.1016/j.jconrel.2013.06.021. Epub 2013 Jun 22. J Control Release. 2013. PMID: 23800420 Free article.

3

Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies.

Dengl S, Hoffmann E, Grote M, Wagner C, Mundigl O, Georges G, Thorey I, Stubenrauch KG, Bujotzek A, Josel HP, Dziadek S, Benz J, Brinkmann U. Dengl S, et al. FASEB J. 2015 May;29(5):1763-79. doi: 10.1096/fj.14-263665. Epub 2015 Feb 10. FASEB J. 2015. PMID: 25670234 Free PMC article.

4

Oxidation in the complementarity-determining regions differentially influences the properties of therapeutic antibodies.

Dashivets T, Stracke J, Dengl S, Knaupp A, Pollmann J, Buchner J, Schlothauer T. Dashivets T, et al. Among authors: dengl s. MAbs. 2016 Nov/Dec;8(8):1525-1535. doi: 10.1080/19420862.2016.1231277. Epub 2016 Sep 9. MAbs. 2016. PMID: 27612038 Free PMC article.

5

Aggregation and chemical modification of monoclonal antibodies under upstream processing conditions.

Dengl S, Wehmer M, Hesse F, Lipsmeier F, Popp O, Lang K. Dengl S, et al. Pharm Res. 2013 May;30(5):1380-99. doi: 10.1007/s11095-013-0977-8. Epub 2013 Jan 16. Pharm Res. 2013. PMID: 23322133

6

Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices.

Dengl S, Mayer K, Bormann F, Duerr H, Hoffmann E, Nussbaum B, Tischler M, Wagner M, Kuglstatter A, Leibrock L, Buldun C, Georges G, Brinkmann U. Dengl S, et al. Nat Commun. 2020 Oct 2;11(1):4974. doi: 10.1038/s41467-020-18477-7. Nat Commun. 2020. PMID: 33009381 Free PMC article.

7

The Contorsbody, an antibody format for agonism: Design, structure, and function.

Georges GJ, Dengl S, Bujotzek A, Hesse F, Fischer JAA, Gärtner A, Benz J, Lauer ME, Ringler P, Stahlberg H, Plath F, Brinkmann U, Imhof-Jung S. Georges GJ, et al. Among authors: dengl s. Comput Struct Biotechnol J. 2020 May 14;18:1210-1220. doi: 10.1016/j.csbj.2020.05.007. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 32542107 Free PMC article.

8

Engineered hapten-binding antibody derivatives for modulation of pharmacokinetic properties of small molecules and targeted payload delivery.

Dengl S, Sustmann C, Brinkmann U. Dengl S, et al. Immunol Rev. 2016 Mar;270(1):165-77. doi: 10.1111/imr.12386. Immunol Rev. 2016. PMID: 26864111 Free PMC article. Review.

9

Interplay between reversible phosphorylation and irreversible ADP-ribosylation of eukaryotic translation elongation factor 2.

Mateus-Seidl R, Stahl S, Dengl S, Birzele F, Herrmuth H, Mayer K, Niederfellner G, Liu XF, Pastan I, Brinkmann U. Mateus-Seidl R, et al. Among authors: dengl s. Biol Chem. 2019 Mar 26;400(4):501-512. doi: 10.1515/hsz-2018-0280. Biol Chem. 2019. PMID: 30218597 Free PMC article.

10

Allosteric antibody inhibition of human hepsin protease.

Koschubs T, Dengl S, Dürr H, Kaluza K, Georges G, Hartl C, Jennewein S, Lanzendörfer M, Auer J, Stern A, Huang KS, Packman K, Gubler U, Kostrewa D, Ries S, Hansen S, Kohnert U, Cramer P, Mundigl O. Koschubs T, et al. Among authors: dengl s. Biochem J. 2012 Mar 15;442(3):483-94. doi: 10.1042/BJ20111317. Biochem J. 2012. PMID: 22132769

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