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A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs.
Liu Z, Zhou J, Xu W, Deng W, Wang Y, Wang M, Wang Q, Hsieh M, Dong J, Wang X, Huang W, Xing L, He M, Tao C, Xie Y, Zhang Y, Wang Y, Zhao J, Yuan Z, Qin C, Jiang S, Lu L. Liu Z, et al. Among authors: deng w. Cell Res. 2022 Mar;32(3):269-287. doi: 10.1038/s41422-022-00612-2. Epub 2022 Jan 19. Cell Res. 2022. PMID: 35046518 Free PMC article.
Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2.
Wang H, Zhang Y, Huang B, Deng W, Quan Y, Wang W, Xu W, Zhao Y, Li N, Zhang J, Liang H, Bao L, Xu Y, Ding L, Zhou W, Gao H, Liu J, Niu P, Zhao L, Zhen W, Fu H, Yu S, Zhang Z, Xu G, Li C, Lou Z, Xu M, Qin C, Wu G, Gao GF, Tan W, Yang X. Wang H, et al. Among authors: deng w. Cell. 2020 Aug 6;182(3):713-721.e9. doi: 10.1016/j.cell.2020.06.008. Epub 2020 Jun 6. Cell. 2020. PMID: 32778225 Free PMC article.
Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Du S, Cao Y, Zhu Q, Yu P, Qi F, Wang G, Du X, Bao L, Deng W, Zhu H, Liu J, Nie J, Zheng Y, Liang H, Liu R, Gong S, Xu H, Yisimayi A, Lv Q, Wang B, He R, Han Y, Zhao W, Bai Y, Qu Y, Gao X, Ji C, Wang Q, Gao N, Huang W, Wang Y, Xie XS, Su XD, Xiao J, Qin C. Du S, et al. Among authors: deng w. Cell. 2020 Nov 12;183(4):1013-1023.e13. doi: 10.1016/j.cell.2020.09.035. Epub 2020 Sep 14. Cell. 2020. PMID: 32970990 Free PMC article.
Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells.
Cao Y, Su B, Guo X, Sun W, Deng Y, Bao L, Zhu Q, Zhang X, Zheng Y, Geng C, Chai X, He R, Li X, Lv Q, Zhu H, Deng W, Xu Y, Wang Y, Qiao L, Tan Y, Song L, Wang G, Du X, Gao N, Liu J, Xiao J, Su XD, Du Z, Feng Y, Qin C, Qin C, Jin R, Xie XS. Cao Y, et al. Among authors: deng y, deng w. Cell. 2020 Jul 9;182(1):73-84.e16. doi: 10.1016/j.cell.2020.05.025. Epub 2020 May 18. Cell. 2020. PMID: 32425270 Free PMC article.
A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity.
Yang J, Wang W, Chen Z, Lu S, Yang F, Bi Z, Bao L, Mo F, Li X, Huang Y, Hong W, Yang Y, Zhao Y, Ye F, Lin S, Deng W, Chen H, Lei H, Zhang Z, Luo M, Gao H, Zheng Y, Gong Y, Jiang X, Xu Y, Lv Q, Li D, Wang M, Li F, Wang S, Wang G, Yu P, Qu Y, Yang L, Deng H, Tong A, Li J, Wang Z, Yang J, Shen G, Zhao Z, Li Y, Luo J, Liu H, Yu W, Yang M, Xu J, Wang J, Li H, Wang H, Kuang D, Lin P, Hu Z, Guo W, Cheng W, He Y, Song X, Chen C, Xue Z, Yao S, Chen L, Ma X, Chen S, Gou M, Huang W, Wang Y, Fan C, Tian Z, Shi M, Wang FS, Dai L, Wu M, Li G, Wang G, Peng Y, Qian Z, Huang C, Lau JY, Yang Z, Wei Y, Cen X, Peng X, Qin C, Zhang K, Lu G, Wei X. Yang J, et al. Among authors: deng h, deng w. Nature. 2020 Oct;586(7830):572-577. doi: 10.1038/s41586-020-2599-8. Epub 2020 Jul 29. Nature. 2020. PMID: 32726802
Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques.
Gao CC, Li M, Deng W, Ma CH, Chen YS, Sun YQ, Du T, Liu QL, Li WJ, Zhang B, Sun L, Liu SM, Li F, Qi F, Qu Y, Ge X, Liu J, Wang P, Niu Y, Liang Z, Zhao YL, Huang B, Peng XZ, Yang Y, Qin C, Tong WM, Yang YG. Gao CC, et al. Among authors: deng w. Protein Cell. 2022 Dec;13(12):920-939. doi: 10.1007/s13238-022-00915-5. Epub 2022 Apr 4. Protein Cell. 2022. PMID: 35377064 Free PMC article.
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Guo Q, Zhao Y, Li J, Liu J, Yang X, Guo X, Kuang M, Xia H, Zhang Z, Cao L, Luo Y, Bao L, Wang X, Wei X, Deng W, Wang N, Chen L, Chen J, Zhu H, Gao R, Qin C, Wang X, You F. Guo Q, et al. Among authors: deng w. Cell Host Microbe. 2021 Feb 10;29(2):222-235.e4. doi: 10.1016/j.chom.2020.12.016. Epub 2020 Dec 26. Cell Host Microbe. 2021. PMID: 33388094 Free PMC article.
SARS-CoV-2 leads to myocardial injury in rhesus macaque.
Feng Y, Song X, Huang Y, Deng W, Li M, Guo X, Qin C, Tong WM, Liu J, Wang J. Feng Y, et al. Among authors: deng w. Signal Transduct Target Ther. 2021 Sep 6;6(1):338. doi: 10.1038/s41392-021-00747-5. Signal Transduct Target Ther. 2021. PMID: 34489396 Free PMC article. No abstract available.
6,152 results