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LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.
Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, He L, Chen Y, Chen H, Luo W, Lu Z, Xie J, Churchill H, Xu Y, Zhou Z, Wu G, Yu C, John S, Hirayasu K, Nguyen N, Liu X, Huang F, Li L, Deng H, Tang H, Sadek AH, Zhang L, Huang T, Zou Y, Chen B, Zhu H, Arase H, Xia N, Jiang Y, Collins R, You MJ, Homsi J, Unni N, Lewis C, Chen GQ, Fu YX, Liao XC, An Z, Zheng J, Zhang N, Zhang CC. Deng M, et al. Among authors: deng h. Nature. 2018 Oct;562(7728):605-609. doi: 10.1038/s41586-018-0615-z. Epub 2018 Oct 17. Nature. 2018. PMID: 30333625 Free PMC article.
A motif in LILRB2 critical for Angptl2 binding and activation.
Deng M, Lu Z, Zheng J, Wan X, Chen X, Hirayasu K, Sun H, Lam Y, Chen L, Wang Q, Song C, Huang N, Gao GF, Jiang Y, Arase H, Zhang CC. Deng M, et al. Blood. 2014 Aug 7;124(6):924-35. doi: 10.1182/blood-2014-01-549162. Epub 2014 Jun 4. Blood. 2014. PMID: 24899623 Free PMC article.
A Novel Anti-LILRB4 CAR-T Cell for the Treatment of Monocytic AML.
John S, Chen H, Deng M, Gui X, Wu G, Chen W, Li Z, Zhang N, An Z, Zhang CC. John S, et al. Among authors: deng m. Mol Ther. 2018 Oct 3;26(10):2487-2495. doi: 10.1016/j.ymthe.2018.08.001. Epub 2018 Aug 7. Mol Ther. 2018. PMID: 30131301 Free PMC article.
Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development.
Gui X, Deng M, Song H, Chen Y, Xie J, Li Z, He L, Huang F, Xu Y, Anami Y, Yu H, Yu C, Li L, Yuan Z, Xu X, Wang Q, Chai Y, Huang T, Shi Y, Tsuchikama K, Liao XC, Xia N, Gao GF, Zhang N, Zhang CC, An Z. Gui X, et al. Among authors: deng m. Cancer Immunol Res. 2019 Aug;7(8):1244-1257. doi: 10.1158/2326-6066.CIR-19-0036. Epub 2019 Jun 18. Cancer Immunol Res. 2019. PMID: 31213474 Free PMC article.
4,161 results