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Complete biosynthesis of cannabinoids and their unnatural analogues in yeast.
Luo X, Reiter MA, d'Espaux L, Wong J, Denby CM, Lechner A, Zhang Y, Grzybowski AT, Harth S, Lin W, Lee H, Yu C, Shin J, Deng K, Benites VT, Wang G, Baidoo EEK, Chen Y, Dev I, Petzold CJ, Keasling JD. Luo X, et al. Among authors: deng k. Nature. 2019 Mar;567(7746):123-126. doi: 10.1038/s41586-019-0978-9. Epub 2019 Feb 27. Nature. 2019. PMID: 30814733
SbCOMT (Bmr12) is involved in the biosynthesis of tricin-lignin in sorghum.
Eudes A, Dutta T, Deng K, Jacquet N, Sinha A, Benites VT, Baidoo EEK, Richel A, Sattler SE, Northen TR, Singh S, Simmons BA, Loqué D. Eudes A, et al. Among authors: deng k. PLoS One. 2017 Jun 8;12(6):e0178160. doi: 10.1371/journal.pone.0178160. eCollection 2017. PLoS One. 2017. PMID: 28594846 Free PMC article.
Lessons from Two Design-Build-Test-Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning.
Opgenorth P, Costello Z, Okada T, Goyal G, Chen Y, Gin J, Benites V, de Raad M, Northen TR, Deng K, Deutsch S, Baidoo EEK, Petzold CJ, Hillson NJ, Garcia Martin H, Beller HR. Opgenorth P, et al. Among authors: deng k. ACS Synth Biol. 2019 Jun 21;8(6):1337-1351. doi: 10.1021/acssynbio.9b00020. Epub 2019 May 24. ACS Synth Biol. 2019. PMID: 31072100 Free article.
Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase.
Englund E, Schmidt M, Nava AA, Lechner A, Deng K, Jocic R, Lin Y, Roberts J, Benites VT, Kakumanu R, Gin JW, Chen Y, Liu Y, Petzold CJ, Baidoo EEK, Northen TR, Adams PD, Katz L, Yuzawa S, Keasling JD. Englund E, et al. Among authors: deng k. J Am Chem Soc. 2023 Apr 26;145(16):8822-8832. doi: 10.1021/jacs.2c11027. Epub 2023 Apr 14. J Am Chem Soc. 2023. PMID: 37057992 Free PMC article.
Complete integration of carbene-transfer chemistry into biosynthesis.
Huang J, Quest A, Cruz-Morales P, Deng K, Pereira JH, Van Cura D, Kakumanu R, Baidoo EEK, Dan Q, Chen Y, Petzold CJ, Northen TR, Adams PD, Clark DS, Balskus EP, Hartwig JF, Mukhopadhyay A, Keasling JD. Huang J, et al. Among authors: deng k. Nature. 2023 May;617(7960):403-408. doi: 10.1038/s41586-023-06027-2. Epub 2023 May 3. Nature. 2023. PMID: 37138074
2,090 results