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The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.
Xia Y, Xie Y, Yu Z, Xiao H, Jiang G, Zhou X, Yang Y, Li X, Zhao M, Li L, Zheng M, Han S, Zong Z, Meng X, Deng H, Ye H, Fa Y, Wu H, Oldfield E, Hu X, Liu W, Shi Y, Zhang Y. Xia Y, et al. Among authors: deng h. Cell. 2018 Nov 1;175(4):1059-1073.e21. doi: 10.1016/j.cell.2018.08.070. Epub 2018 Sep 27. Cell. 2018. PMID: 30270039 Free article.
Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L. Cheng L, et al. Among authors: deng h. Arch Toxicol. 2018 Jan;92(1):469-485. doi: 10.1007/s00204-017-2048-0. Epub 2017 Sep 4. Arch Toxicol. 2018. PMID: 28871336 Free PMC article.
Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy.
Wang L, Shao X, Zhong T, Wu Y, Xu A, Sun X, Gao H, Liu Y, Lan T, Tong Y, Tao X, Du W, Wang W, Chen Y, Li T, Meng X, Deng H, Yang B, He Q, Ying M, Rao Y. Wang L, et al. Among authors: deng h. Nat Chem Biol. 2021 May;17(5):567-575. doi: 10.1038/s41589-021-00742-5. Epub 2021 Mar 4. Nat Chem Biol. 2021. PMID: 33664520
9,125 results