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A microfluidic mechano-chemostat for tissues and organisms reveals that confined growth is accompanied with increased macromolecular crowding.
Ben Meriem Z, Mateo T, Faccini J, Denais C, Dusfour-Castan R, Guynet C, Merle T, Suzanne M, Di-Luoffo M, Guillermet-Guibert J, Alric B, Landiech S, Malaquin L, Mesnilgrente F, Laborde A, Mazenq L, Courson R, Delarue M. Ben Meriem Z, et al. Among authors: denais c. Lab Chip. 2023 Oct 10;23(20):4445-4455. doi: 10.1039/d3lc00313b. Lab Chip. 2023. PMID: 37740366
Cell-intrinsic differences between human airway epithelial cells from children and adults.
Maughan EF, Hynds RE, Pennycuick A, Nigro E, Gowers KHC, Denais C, Gómez-López S, Lazarus KA, Orr JC, Pearce DR, Clarke SE, Lee DDH, Woodall MNJ, Masonou T, Case KM, Teixeira VH, Hartley BE, Hewitt RJ, Al Yaghchi C, Sandhu GS, Birchall MA, O'Callaghan C, Smith CM, De Coppi P, Butler CR, Janes SM. Maughan EF, et al. Among authors: denais c. iScience. 2022 Oct 20;25(11):105409. doi: 10.1016/j.isci.2022.105409. eCollection 2022 Nov 18. iScience. 2022. PMID: 36388965 Free PMC article.
Immune Surveillance in Clinical Regression of Preinvasive Squamous Cell Lung Cancer.
Pennycuick A, Teixeira VH, AbdulJabbar K, Raza SEA, Lund T, Akarca AU, Rosenthal R, Kalinke L, Chandrasekharan DP, Pipinikas CP, Lee-Six H, Hynds RE, Gowers KHC, Henry JY, Millar FR, Hagos YB, Denais C, Falzon M, Moore DA, Antoniou S, Durrenberger PF, Furness AJ, Carroll B, Marceaux C, Asselin-Labat ML, Larson W, Betts C, Coussens LM, Thakrar RM, George J, Swanton C, Thirlwell C, Campbell PJ, Marafioti T, Yuan Y, Quezada SA, McGranahan N, Janes SM. Pennycuick A, et al. Among authors: denais c. Cancer Discov. 2020 Oct;10(10):1489-1499. doi: 10.1158/2159-8290.CD-19-1366. Epub 2020 Jul 20. Cancer Discov. 2020. PMID: 32690541 Free PMC article.
Nuclear envelope rupture and repair during cancer cell migration.
Denais CM, Gilbert RM, Isermann P, McGregor AL, te Lindert M, Weigelin B, Davidson PM, Friedl P, Wolf K, Lammerding J. Denais CM, et al. Science. 2016 Apr 15;352(6283):353-8. doi: 10.1126/science.aad7297. Epub 2016 Mar 24. Science. 2016. PMID: 27013428 Free PMC article.
Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion.
Thomas DG, Yenepalli A, Denais CM, Rape A, Beach JR, Wang YL, Schiemann WP, Baskaran H, Lammerding J, Egelhoff TT. Thomas DG, et al. Among authors: denais cm. J Cell Biol. 2015 Aug 17;210(4):583-94. doi: 10.1083/jcb.201502039. Epub 2015 Aug 10. J Cell Biol. 2015. PMID: 26261182 Free PMC article.
Nuclear mechanics in cancer.
Denais C, Lammerding J. Denais C, et al. Adv Exp Med Biol. 2014;773:435-70. doi: 10.1007/978-1-4899-8032-8_20. Adv Exp Med Biol. 2014. PMID: 24563360 Free PMC article. Review.
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