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Transcription-coupled DNA-protein crosslink repair by CSB and CRL4CSA-mediated degradation.
van Sluis M, Yu Q, van der Woude M, Gonzalo-Hansen C, Dealy SC, Janssens RC, Somsen HB, Ramadhin AR, Dekkers DHW, Wienecke HL, Demmers JJPG, Raams A, Davó-Martínez C, Llerena Schiffmacher DA, van Toorn M, Häckes D, Thijssen KL, Zhou D, Lammers JG, Pines A, Vermeulen W, Pothof J, Demmers JAA, van den Berg DLC, Lans H, Marteijn JA. van Sluis M, et al. Among authors: demmers jjpg, demmers jaa. Nat Cell Biol. 2024 Apr 10. doi: 10.1038/s41556-024-01394-y. Online ahead of print. Nat Cell Biol. 2024. PMID: 38600236
PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency.
Crespo R, Ne E, Reinders J, Meier JIJ, Li C, Jansen S, Górska A, Koçer S, Kan TW, Doff W, Dekkers D, Demmers J, Palstra RJ, Rao S, Mahmoudi T. Crespo R, et al. Among authors: demmers j. iScience. 2024 Feb 6;27(3):109152. doi: 10.1016/j.isci.2024.109152. eCollection 2024 Mar 15. iScience. 2024. PMID: 38384833 Free PMC article.
Chromatin targeting of the RNF12/RLIM E3 ubiquitin ligase controls transcriptional responses.
Espejo-Serrano C, Aitken C, Tan BF, May DG, Chrisopulos RJ, Roux KJ, Demmers JA, Mackintosh SG, Gribnau J, Bustos F, Gontan C, Findlay GM. Espejo-Serrano C, et al. Among authors: demmers ja. Life Sci Alliance. 2024 Jan 10;7(3):e202302282. doi: 10.26508/lsa.202302282. Print 2024 Mar. Life Sci Alliance. 2024. PMID: 38199845 Free PMC article.
Matrix Metalloproteinase-7 in Urinary Extracellular Vesicles Identifies Rapid Disease Progression in Autosomal Dominant Polycystic Kidney Disease.
van Heugten MH, Blijdorp CJ, Arjune S, van Willigenburg H, Bezstarosti K, Demmers JAA, Musterd-Bhaggoe U, Meijer E, Gansevoort RT, Zietse R, Hayat S, Kramann R, Müller RU, Salih M, Hoorn EJ; DIPAK Consortium. van Heugten MH, et al. Among authors: demmers jaa. J Am Soc Nephrol. 2024 Mar 1;35(3):321-334. doi: 10.1681/ASN.0000000000000277. Epub 2023 Dec 11. J Am Soc Nephrol. 2024. PMID: 38073039
DDA1, a novel factor in transcription-coupled repair, modulates CRL4CSA dynamics at DNA damage-stalled RNA polymerase II.
Schiffmacher DL, Lee SH, Kliza KW, Theil AF, Akita M, Helfricht A, Bezstarosti K, Gonzalo-Hansen C, van Attikum H, Verlaan-de Vries M, Vertegaal ACO, Hoeijmakers JHJ, Marteijn JA, Lans H, Demmers JAA, Vermeulen M, Sixma T, Ogi T, Vermeulen W, Pines A. Schiffmacher DL, et al. Among authors: demmers jaa. Res Sq [Preprint]. 2023 Oct 12:rs.3.rs-3385435. doi: 10.21203/rs.3.rs-3385435/v1. Res Sq. 2023. PMID: 37886519 Free PMC article. Preprint.
Trichothiodystrophy-associated MPLKIP maintains DBR1 levels for proper lariat debranching and ectodermal differentiation.
Theil AF, Pines A, Kalayci T, Heredia-Genestar JM, Raams A, Rietveld MH, Sridharan S, Tanis SE, Mulder KW, Büyükbabani N, Karaman B, Uyguner ZO, Kayserili H, Hoeijmakers JH, Lans H, Demmers JA, Pothof J, Altunoglu U, El Ghalbzouri A, Vermeulen W. Theil AF, et al. Among authors: demmers ja. EMBO Mol Med. 2023 Nov 8;15(11):e17973. doi: 10.15252/emmm.202317973. Epub 2023 Oct 6. EMBO Mol Med. 2023. PMID: 37800682 Free PMC article.
High-throughput Proteomics Identifies THEMIS2 as Independent Biomarker of Treatment-free Survival in Untreated CLL.
Hengeveld PJ, Kolijn PM, Demmers JAA, Doff W, Dubois JMN, Rijken M, Assmann JLJC, van der Straten L, Boiten HJ, Gussinklo KJ, Valk PJM, Faber LM, Westerweel PE, Kater AP, Levin MD, Langerak AW. Hengeveld PJ, et al. Among authors: demmers jaa. Hemasphere. 2023 Sep 15;7(10):e951. doi: 10.1097/HS9.0000000000000951. eCollection 2023 Oct. Hemasphere. 2023. PMID: 37731707 Free PMC article.
Live cell transcription-coupled nucleotide excision repair dynamics revisited.
Llerena Schiffmacher DA, Kliza KW, Theil AF, Kremers GJ, Demmers JAA, Ogi T, Vermeulen M, Vermeulen W, Pines A. Llerena Schiffmacher DA, et al. Among authors: demmers jaa. DNA Repair (Amst). 2023 Oct;130:103566. doi: 10.1016/j.dnarep.2023.103566. Epub 2023 Sep 9. DNA Repair (Amst). 2023. PMID: 37716192 Free article.
210 results