Demetri GD - Search Results

1

Concurrent inhibition of CDK2 adds to the anti-tumour activity of CDK4/6 inhibition in GIST.

Schaefer IM, Hemming ML, Lundberg MZ, Serrata MP, Goldaracena I, Liu N, Yin P, Paulo JA, Gygi SP, George S, Morgan JA, Bertagnolli MM, Sicinska ET, Chu C, Zheng S, Mariño-Enríquez A, Hornick JL, Raut CP, Ou WB, Demetri GD, Saka SK, Fletcher JA. Schaefer IM, et al. Among authors: demetri gd. Br J Cancer. 2022 Nov;127(11):2072-2085. doi: 10.1038/s41416-022-01990-5. Epub 2022 Sep 29. Br J Cancer. 2022. PMID: 36175617 Free PMC article.

2

Synovial sarcoma: prognostic significance of tumor size, margin of resection, and mitotic activity for survival.

Singer S, Baldini EH, Demetri GD, Fletcher JA, Corson JM. Singer S, et al. Among authors: demetri gd. J Clin Oncol. 1996 Apr;14(4):1201-8. doi: 10.1200/JCO.1996.14.4.1201. J Clin Oncol. 1996. PMID: 8648375

3

KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors.

Lux ML, Rubin BP, Biase TL, Chen CJ, Maclure T, Demetri G, Xiao S, Singer S, Fletcher CD, Fletcher JA. Lux ML, et al. Am J Pathol. 2000 Mar;156(3):791-5. doi: 10.1016/S0002-9440(10)64946-2. Am J Pathol. 2000. PMID: 10702394 Free PMC article.

4

STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications.

Tuveson DA, Willis NA, Jacks T, Griffin JD, Singer S, Fletcher CD, Fletcher JA, Demetri GD. Tuveson DA, et al. Among authors: demetri gd. Oncogene. 2001 Aug 16;20(36):5054-8. doi: 10.1038/sj.onc.1204704. Oncogene. 2001. PMID: 11526490

5

KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.

Rubin BP, Singer S, Tsao C, Duensing A, Lux ML, Ruiz R, Hibbard MK, Chen CJ, Xiao S, Tuveson DA, Demetri GD, Fletcher CD, Fletcher JA. Rubin BP, et al. Among authors: demetri gd. Cancer Res. 2001 Nov 15;61(22):8118-21. Cancer Res. 2001. PMID: 11719439

6

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors.

Demetri GD, von Mehren M, Blanke CD, Van den Abbeele AD, Eisenberg B, Roberts PJ, Heinrich MC, Tuveson DA, Singer S, Janicek M, Fletcher JA, Silverman SG, Silberman SL, Capdeville R, Kiese B, Peng B, Dimitrijevic S, Druker BJ, Corless C, Fletcher CD, Joensuu H. Demetri GD, et al. N Engl J Med. 2002 Aug 15;347(7):472-80. doi: 10.1056/NEJMoa020461. N Engl J Med. 2002. PMID: 12181401 Free article. Clinical Trial.

7

Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors.

Singer S, Rubin BP, Lux ML, Chen CJ, Demetri GD, Fletcher CD, Fletcher JA. Singer S, et al. Among authors: demetri gd. J Clin Oncol. 2002 Sep 15;20(18):3898-905. doi: 10.1200/JCO.2002.03.095. J Clin Oncol. 2002. PMID: 12228211

8

PDGFRA activating mutations in gastrointestinal stromal tumors.

Heinrich MC, Corless CL, Duensing A, McGreevey L, Chen CJ, Joseph N, Singer S, Griffith DJ, Haley A, Town A, Demetri GD, Fletcher CD, Fletcher JA. Heinrich MC, et al. Among authors: demetri gd. Science. 2003 Jan 31;299(5607):708-10. doi: 10.1126/science.1079666. Epub 2003 Jan 9. Science. 2003. PMID: 12522257

9

Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs).

Duensing A, Medeiros F, McConarty B, Joseph NE, Panigrahy D, Singer S, Fletcher CD, Demetri GD, Fletcher JA. Duensing A, et al. Among authors: demetri gd. Oncogene. 2004 May 13;23(22):3999-4006. doi: 10.1038/sj.onc.1207525. Oncogene. 2004. PMID: 15007386

10

Protein Kinase C theta (PKCtheta) expression and constitutive activation in gastrointestinal stromal tumors (GISTs).

Duensing A, Joseph NE, Medeiros F, Smith F, Hornick JL, Heinrich MC, Corless CL, Demetri GD, Fletcher CD, Fletcher JA. Duensing A, et al. Among authors: demetri gd. Cancer Res. 2004 Aug 1;64(15):5127-31. doi: 10.1158/0008-5472.CAN-04-0559. Cancer Res. 2004. PMID: 15289315

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