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Mechanistic Insights into the Leishmanicidal and Bactericidal Activities of Batroxicidin, a Cathelicidin-Related Peptide from a South American Viper (Bothrops atrox).
Dematei A, Nunes JB, Moreira DC, Jesus JA, Laurenti MD, Mengarda ACA, Vieira MS, do Amaral CP, Domingues MM, de Moraes J, Passero LFD, Brand G, Bessa LJ, Wimmer R, Kuckelhaus SAS, Tomás AM, Santos NC, Plácido A, Eaton P, Leite JRSA. Dematei A, et al. J Nat Prod. 2021 Jun 25;84(6):1787-1798. doi: 10.1021/acs.jnatprod.1c00153. Epub 2021 Jun 2. J Nat Prod. 2021. PMID: 34077221
The peptide secreted at the water to land transition in a model amphibian has antioxidant effects.
Barbosa EA, Plácido A, Moreira DC, Albuquerque L, Dematei A, Silva-Carvalho AÉ, Cabral WF, Báo SN, Saldanha-Araújo F, Kuckelhaus SAS, Borges TK, Portugal CC, Socodato R, Teixeira C, Lima FCDA, Batagin-Neto A, Sebben A, Eaton P, Gomes P, Brand GD, Relvas JB, Kato MJ, Leite JRSA. Barbosa EA, et al. Among authors: dematei a. Proc Biol Sci. 2021 Nov 10;288(1962):20211531. doi: 10.1098/rspb.2021.1531. Epub 2021 Nov 10. Proc Biol Sci. 2021. PMID: 34753356 Free PMC article.
Structural Characterization and Rat Aortic Vascular Reactivity of Bradykinin-Potentiating Peptides (BPPs) from the Snake Venom of Bothrops moojeni from Delta do Parnaíba Region, Brazil.
Costa SR, Vasconcelos AG, Almeida JOCS, Arcanjo DDR, Dematei A, Barbosa EA, Silva PC, Nascimento T, Santos LH, Eaton P, Leite JRSA, Brand GD. Costa SR, et al. Among authors: dematei a. J Nat Prod. 2024 Apr 26;87(4):820-830. doi: 10.1021/acs.jnatprod.3c00991. Epub 2024 Mar 6. J Nat Prod. 2024. PMID: 38449376
Antioxidant and Neuroprotective Effects of the First Tryptophyllin Found in Snake Venom (Bothrops moojeni).
Dematei A, Costa SR, Moreira DC, Barbosa EA, Friaça Albuquerque LF, Vasconcelos AG, Nascimento T, Silva PC, Silva-Carvalho AÉ, Saldanha-Araújo F, Silva Mancini MC, Saboia Ponte LG, Neves Bezerra RM, Simabuco FM, Batagin-Neto A, Brand G, Borges TKS, Eaton P, Leite JRSA. Dematei A, et al. J Nat Prod. 2022 Dec 23;85(12):2695-2705. doi: 10.1021/acs.jnatprod.2c00304. Epub 2022 Dec 12. J Nat Prod. 2022. PMID: 36508333