Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation.
Valiente E, Bouché L, Hitchen P, Faulds-Pain A, Songane M, Dawson LF, Donahue E, Stabler RA, Panico M, Morris HR, Bajaj-Elliott M, Logan SM, Dell A, Wren BW.
Valiente E, et al. Among authors: dell a.
J Biol Chem. 2016 Dec 2;291(49):25450-25461. doi: 10.1074/jbc.M116.749523. Epub 2016 Oct 4.
J Biol Chem. 2016.
PMID: 27703012
Free PMC article.
Clostridium difficile is the principal cause of nosocomial infectious diarrhea worldwide. The pathogen modifies its flagellin with either a type A or type B O-linked glycosylation system, which has a contributory role in pathogenesis. ...M., Wren, B. W., D …
Clostridium difficile is the principal cause of nosocomial infectious diarrhea worldwide. The pathogen modifies its flagellin with either …