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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake.
McEwan AR, Davidson C, Hay E, Turnbull Y, Erickson JC, Marini P, Wilson D, McIntosh AM, Adams MJ, Murgatroyd C, Barrett P, Delibegovic M, Clarke TK, MacKenzie A. McEwan AR, et al. Among authors: delibegovic m. Mol Psychiatry. 2021 Jun;26(6):2263-2276. doi: 10.1038/s41380-020-0707-7. Epub 2020 Mar 13. Mol Psychiatry. 2021. PMID: 32203157
Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE-/- mouse model of atherosclerosis with alterations in IL10/AMPKα pathway.
Thompson D, Morrice N, Grant L, Le Sommer S, Ziegler K, Whitfield P, Mody N, Wilson HM, Delibegović M. Thompson D, et al. Among authors: delibegovic m. Mol Metab. 2017 Jun 13;6(8):845-853. doi: 10.1016/j.molmet.2017.06.003. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752048 Free PMC article.
The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice.
Dekeryte R, Franklin Z, Hull C, Croce L, Kamli-Salino S, Helk O, Hoffmann PA, Yang Z, Riedel G, Delibegovic M, Platt B. Dekeryte R, et al. Among authors: delibegovic m. Biochim Biophys Acta Mol Basis Dis. 2021 Jul 1;1867(7):166149. doi: 10.1016/j.bbadis.2021.166149. Epub 2021 Apr 20. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33892080 Free article.
A key role for PTP1B in dendritic cell maturation, migration, and T cell activation.
Martin-Granados C, Prescott AR, Le Sommer S, Klaska IP, Yu T, Muckersie E, Giuraniuc CV, Grant L, Delibegovic M, Forrester JV. Martin-Granados C, et al. Among authors: delibegovic m. J Mol Cell Biol. 2015 Dec;7(6):517-28. doi: 10.1093/jmcb/mjv032. Epub 2015 Jun 10. J Mol Cell Biol. 2015. PMID: 26063615
71 results