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Novel thiosemicarbazones induce high toxicity in estrogen-receptor-positive breast cancer cells (MCF7) and exacerbate cisplatin effectiveness in triple-negative breast (MDA-MB231) and lung adenocarcinoma (A549) cells.
Medina-Reyes EI, Mancera-Rodríguez MA, Delgado-Buenrostro NL, Moreno-Rodríguez A, Bautista-Martínez JL, Díaz-Velásquez CE, Martínez-Alarcón SA, Torrens H, de Los Ángeles Godínez-Rodríguez M, Terrazas-Valdés LI, Chirino YI, Vaca-Paniagua F. Medina-Reyes EI, et al. Invest New Drugs. 2020 Jun;38(3):558-573. doi: 10.1007/s10637-019-00789-1. Epub 2019 Jun 8. Invest New Drugs. 2020. PMID: 31177399
Titanium dioxide nanoparticles impair lung mitochondrial function.
Freyre-Fonseca V, Delgado-Buenrostro NL, Gutiérrez-Cirlos EB, Calderón-Torres CM, Cabellos-Avelar T, Sánchez-Pérez Y, Pinzón E, Torres I, Molina-Jijón E, Zazueta C, Pedraza-Chaverri J, García-Cuéllar CM, Chirino YI. Freyre-Fonseca V, et al. Toxicol Lett. 2011 Apr 25;202(2):111-9. doi: 10.1016/j.toxlet.2011.01.025. Epub 2011 Feb 15. Toxicol Lett. 2011. PMID: 21315139
Nrf2 protects the lung against inflammation induced by titanium dioxide nanoparticles: A positive regulator role of Nrf2 on cytokine release.
Delgado-Buenrostro NL, Medina-Reyes EI, Lastres-Becker I, Freyre-Fonseca V, Ji Z, Hernández-Pando R, Marquina B, Pedraza-Chaverri J, Espada S, Cuadrado A, Chirino YI. Delgado-Buenrostro NL, et al. Environ Toxicol. 2015 Jul;30(7):782-92. doi: 10.1002/tox.21957. Epub 2014 Feb 26. Environ Toxicol. 2015. PMID: 24615891
Titanium dioxide nanoparticles induce an adaptive inflammatory response and invasion and proliferation of lung epithelial cells in chorioallantoic membrane.
Medina-Reyes EI, Déciga-Alcaraz A, Freyre-Fonseca V, Delgado-Buenrostro NL, Flores-Flores JO, Gutiérrez-López GF, Sánchez-Pérez Y, García-Cuéllar CM, Pedraza-Chaverri J, Chirino YI. Medina-Reyes EI, et al. Environ Res. 2015 Jan;136:424-34. doi: 10.1016/j.envres.2014.10.016. Epub 2014 Nov 25. Environ Res. 2015. PMID: 25460664
Food-grade titanium dioxide exposure exacerbates tumor formation in colitis associated cancer model.
Urrutia-Ortega IM, Garduño-Balderas LG, Delgado-Buenrostro NL, Freyre-Fonseca V, Flores-Flores JO, González-Robles A, Pedraza-Chaverri J, Hernández-Pando R, Rodríguez-Sosa M, León-Cabrera S, Terrazas LI, van Loveren H, Chirino YI. Urrutia-Ortega IM, et al. Food Chem Toxicol. 2016 Jul;93:20-31. doi: 10.1016/j.fct.2016.04.014. Epub 2016 Apr 23. Food Chem Toxicol. 2016. PMID: 27117919
45 results