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109 results

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Page 1
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression.
Juárez-Fernández M, Goikoetxea-Usandizaga N, Porras D, García-Mediavilla MV, Bravo M, Serrano-Maciá M, Simón J, Delgado TC, Lachiondo-Ortega S, Martínez-Flórez S, Lorenzo Ó, Rincón M, Varela-Rey M, Abecia L, Rodríguez H, Anguita J, Nistal E, Martínez-Chantar ML, Sánchez-Campos S. Juárez-Fernández M, et al. Among authors: delgado tc. Hepatology. 2023 May 1;77(5):1654-1669. doi: 10.1002/hep.32705. Epub 2023 Apr 17. Hepatology. 2023. PMID: 35921199 Free PMC article.
Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer.
Barbier-Torres L, Delgado TC, García-Rodríguez JL, Zubiete-Franco I, Fernández-Ramos D, Buqué X, Cano A, Gutiérrez-de Juan V, Fernández-Domínguez I, Lopitz-Otsoa F, Fernández-Tussy P, Boix L, Bruix J, Villa E, Castro A, Lu SC, Aspichueta P, Xirodimas D, Varela-Rey M, Mato JM, Beraza N, Martínez-Chantar ML. Barbier-Torres L, et al. Among authors: delgado tc. Oncotarget. 2015 Feb 10;6(4):2509-23. doi: 10.18632/oncotarget.3191. Oncotarget. 2015. PMID: 25650664 Free PMC article.
Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1.
Barbier-Torres L, Beraza N, Fernández-Tussy P, Lopitz-Otsoa F, Fernández-Ramos D, Zubiete-Franco I, Varela-Rey M, Delgado TC, Gutiérrez V, Anguita J, Pares A, Banales JM, Villa E, Caballería J, Alvarez L, Lu SC, Mato JM, Martínez-Chantar ML. Barbier-Torres L, et al. Among authors: delgado tc. Hepatology. 2015 Oct;62(4):1237-48. doi: 10.1002/hep.27959. Epub 2015 Jul 31. Hepatology. 2015. PMID: 26109312 Free PMC article.
Deregulated neddylation in liver fibrosis.
Zubiete-Franco I, Fernández-Tussy P, Barbier-Torres L, Simon J, Fernández-Ramos D, Lopitz-Otsoa F, Gutiérrez-de Juan V, de Davalillo SL, Duce AM, Iruzubieta P, Taibo D, Crespo J, Caballeria J, Villa E, Aurrekoetxea I, Aspichueta P, Varela-Rey M, Lu SC, Mato JM, Beraza N, Delgado TC, Martínez-Chantar ML. Zubiete-Franco I, et al. Among authors: delgado tc. Hepatology. 2017 Feb;65(2):694-709. doi: 10.1002/hep.28933. Epub 2016 Dec 30. Hepatology. 2017. PMID: 28035772 Free PMC article.
A morphological method for ammonia detection in liver.
Gutiérrez-de-Juan V, López de Davalillo S, Fernández-Ramos D, Barbier-Torres L, Zubiete-Franco I, Fernández-Tussy P, Simon J, Lopitz-Otsoa F, de Las Heras J, Iruzubieta P, Arias-Loste MT, Villa E, Crespo J, Andrade R, Lucena MI, Varela-Rey M, Lu SC, Mato JM, Delgado TC, Martínez-Chantar ML. Gutiérrez-de-Juan V, et al. Among authors: delgado tc. PLoS One. 2017 Mar 20;12(3):e0173914. doi: 10.1371/journal.pone.0173914. eCollection 2017. PLoS One. 2017. PMID: 28319158 Free PMC article.
Role of Aramchol in steatohepatitis and fibrosis in mice.
Iruarrizaga-Lejarreta M, Varela-Rey M, Fernández-Ramos D, Martínez-Arranz I, Delgado TC, Simon J, Juan VG, delaCruz-Villar L, Azkargorta M, Lavin JL, Mayo R, Van Liempd SM, Aurrekoetxea I, Buqué X, Cave DD, Peña A, Rodríguez-Cuesta J, Aransay AM, Elortza F, Falcón-Pérez JM, Aspichueta P, Hayardeny L, Noureddin M, Sanyal AJ, Alonso C, Anguita J, Martínez-Chantar ML, Lu SC, Mato JM. Iruarrizaga-Lejarreta M, et al. Among authors: delgado tc. Hepatol Commun. 2017 Nov;1(9):911-927. doi: 10.1002/hep4.1107. Epub 2017 Oct 4. Hepatol Commun. 2017. PMID: 29159325 Free PMC article.
The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.
Barbier-Torres L, Iruzubieta P, Fernández-Ramos D, Delgado TC, Taibo D, Guitiérrez-de-Juan V, Varela-Rey M, Azkargorta M, Navasa N, Fernández-Tussy P, Zubiete-Franco I, Simon J, Lopitz-Otsoa F, Lachiondo-Ortega S, Crespo J, Masson S, McCain MV, Villa E, Reeves H, Elortza F, Lucena MI, Hernández-Alvarez MI, Zorzano A, Andrade RJ, Lu SC, Mato JM, Anguita J, Rincón M, Martínez-Chantar ML. Barbier-Torres L, et al. Among authors: delgado tc. Nat Commun. 2017 Dec 12;8(1):2068. doi: 10.1038/s41467-017-01970-x. Nat Commun. 2017. PMID: 29233977 Free PMC article.
Neddylation, a novel paradigm in liver cancer.
Delgado TC, Barbier-Torres L, Zubiete-Franco I, Lopitz-Otsoa F, Varela-Rey M, Fernández-Ramos D, Martínez-Chantar ML. Delgado TC, et al. Transl Gastroenterol Hepatol. 2018 Jun 30;3:37. doi: 10.21037/tgh.2018.06.05. eCollection 2018. Transl Gastroenterol Hepatol. 2018. PMID: 30050997 Free PMC article. Review.
MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis.
Fernández-Ramos D, Fernández-Tussy P, Lopitz-Otsoa F, Gutiérrez-de-Juan V, Navasa N, Barbier-Torres L, Zubiete-Franco I, Simón J, Fernández AF, Arbelaiz A, Aransay AM, Lavín JL, Beraza N, Perugorria MJ, Banales JM, Villa E, Fraga MF, Anguita J, Avila MA, Berasain C, Iruzibieta P, Crespo J, Lu SC, Varela-Rey M, Mato JM, Delgado TC, Martínez-Chantar ML. Fernández-Ramos D, et al. Among authors: delgado tc. Cell Death Dis. 2018 Sep 20;9(10):958. doi: 10.1038/s41419-018-1014-y. Cell Death Dis. 2018. PMID: 30237481 Free PMC article.
SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer.
Zubiete-Franco I, García-Rodríguez JL, Lopitz-Otsoa F, Serrano-Macia M, Simon J, Fernández-Tussy P, Barbier-Torres L, Fernández-Ramos D, Gutiérrez-de-Juan V, López de Davalillo S, Carlevaris O, Beguiristain Gómez A, Villa E, Calvisi D, Martín C, Berra E, Aspichueta P, Beraza N, Varela-Rey M, Ávila M, Rodríguez MS, Mato JM, Díaz-Moreno I, Díaz-Quintana A, Delgado TC, Martínez-Chantar ML. Zubiete-Franco I, et al. Among authors: delgado tc. EBioMedicine. 2019 Feb;40:406-421. doi: 10.1016/j.ebiom.2018.12.031. Epub 2018 Dec 26. EBioMedicine. 2019. PMID: 30594553 Free PMC article.
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