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The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination.
Zahid MN, Turek M, Xiao F, Thi VL, Guérin M, Fofana I, Bachellier P, Thompson J, Delang L, Neyts J, Bankwitz D, Pietschmann T, Dreux M, Cosset FL, Grunert F, Baumert TF, Zeisel MB. Zahid MN, et al. Among authors: delang l. Hepatology. 2013 Feb;57(2):492-504. doi: 10.1002/hep.26097. Epub 2012 Dec 28. Hepatology. 2013. PMID: 23081796 Free article.
Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains.
Aubry F, Jacobs S, Darmuzey M, Lequime S, Delang L, Fontaine A, Jupatanakul N, Miot EF, Dabo S, Manet C, Montagutelli X, Baidaliuk A, Gámbaro F, Simon-Lorière E, Gilsoul M, Romero-Vivas CM, Cao-Lormeau VM, Jarman RG, Diagne CT, Faye O, Faye O, Sall AA, Neyts J, Nguyen L, Kaptein SJF, Lambrechts L. Aubry F, et al. Among authors: delang l. Nat Commun. 2021 Feb 10;12(1):916. doi: 10.1038/s41467-021-21199-z. Nat Commun. 2021. PMID: 33568638 Free PMC article.
Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral.
Delang L, Segura Guerrero N, Tas A, Quérat G, Pastorino B, Froeyen M, Dallmeier K, Jochmans D, Herdewijn P, Bello F, Snijder EJ, de Lamballerie X, Martina B, Neyts J, van Hemert MJ, Leyssen P. Delang L, et al. J Antimicrob Chemother. 2014 Oct;69(10):2770-84. doi: 10.1093/jac/dku209. Epub 2014 Jun 20. J Antimicrob Chemother. 2014. PMID: 24951535
Pan-viral protection against arboviruses by activating skin macrophages at the inoculation site.
Bryden SR, Pingen M, Lefteri DA, Miltenburg J, Delang L, Jacobs S, Abdelnabi R, Neyts J, Pondeville E, Major J, Müller M, Khalid H, Tuplin A, Varjak M, Merits A, Edgar J, Graham GJ, Shams K, McKimmie CS. Bryden SR, et al. Among authors: delang l. Sci Transl Med. 2020 Jan 22;12(527):eaax2421. doi: 10.1126/scitranslmed.aax2421. Sci Transl Med. 2020. PMID: 31969486 Free article.
Inhibition of the Replication of Different Strains of Chikungunya Virus by 3-Aryl-[1,2,3]triazolo[4,5- d]pyrimidin-7(6 H)-ones.
Gómez-SanJuan A, Gamo AM, Delang L, Pérez-Sánchez A, Amrun SN, Abdelnabi R, Jacobs S, Priego EM, Camarasa MJ, Jochmans D, Leyssen P, Ng LFP, Querat G, Neyts J, Pérez-Pérez MJ. Gómez-SanJuan A, et al. Among authors: delang l. ACS Infect Dis. 2018 Apr 13;4(4):605-619. doi: 10.1021/acsinfecdis.7b00219. Epub 2018 Feb 14. ACS Infect Dis. 2018. PMID: 29406692
Antiplasmodial, anti-chikungunya virus and antioxidant activities of 64 endemic plants from the Mascarene Islands.
Ledoux A, Cao M, Jansen O, Mamede L, Campos PE, Payet B, Clerc P, Grondin I, Girard-Valenciennes E, Hermann T, Litaudon M, Vanderheydt C, Delang L, Neyts J, Leyssen P, Frédérich M, Smadja J. Ledoux A, et al. Among authors: delang l. Int J Antimicrob Agents. 2018 Nov;52(5):622-628. doi: 10.1016/j.ijantimicag.2018.07.017. Epub 2018 Jul 29. Int J Antimicrob Agents. 2018. PMID: 30063998
Optimization of a Class of Tryptophan Dendrimers That Inhibit HIV Replication Leads to a Selective, Specific, and Low-Nanomolar Inhibitor of Clinical Isolates of Enterovirus A71.
Rivero-Buceta E, Sun L, Martínez-Gualda B, Doyagüez EG, Donckers K, Quesada E, Camarasa MJ, Delang L, San-Félix A, Neyts J, Leyssen P. Rivero-Buceta E, et al. Among authors: delang l. Antimicrob Agents Chemother. 2016 Jul 22;60(8):5064-7. doi: 10.1128/AAC.00626-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27246775 Free PMC article.
97 results