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Identification of potent and selective small molecule inhibitors of the cation channel TRPM4.
Ozhathil LC, Delalande C, Bianchi B, Nemeth G, Kappel S, Thomet U, Ross-Kaschitza D, Simonin C, Rubin M, Gertsch J, Lochner M, Peinelt C, Reymond JL, Abriel H. Ozhathil LC, et al. Among authors: delalande c. Br J Pharmacol. 2018 Jun;175(12):2504-2519. doi: 10.1111/bph.14220. Epub 2018 Apr 29. Br J Pharmacol. 2018. PMID: 29579323 Free PMC article.
Optimizing TRPM4 inhibitors in the MHFP6 chemical space.
Delalande C, Awale M, Rubin M, Probst D, Ozhathil LC, Gertsch J, Abriel H, Reymond JL. Delalande C, et al. Eur J Med Chem. 2019 Mar 15;166:167-177. doi: 10.1016/j.ejmech.2019.01.048. Epub 2019 Jan 24. Eur J Med Chem. 2019. PMID: 30708257
Frontiers in Medicinal Chemistry 2017 in Bern, Switzerland.
Probst D, Heitz M, Poirier M, Gan BH, Delalande C, Reymond JL. Probst D, et al. Among authors: delalande c. ChemMedChem. 2017 Oct 9;12(19):1645-1651. doi: 10.1002/cmdc.201700306. Epub 2017 Sep 22. ChemMedChem. 2017. PMID: 28941184
Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20.
Azizi SA, Delalande C, Lan T, Qiu T, Dickinson BC. Azizi SA, et al. Among authors: delalande c. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13. ACS Med Chem Lett. 2022. PMID: 36262404 Free PMC article.
Development of an Acrylamide-Based Inhibitor of Protein S-Acylation.
Azizi SA, Lan T, Delalande C, Kathayat RS, Banales Mejia F, Qin A, Brookes N, Sandoval PJ, Dickinson BC. Azizi SA, et al. Among authors: delalande c. ACS Chem Biol. 2021 Aug 20;16(8):1546-1556. doi: 10.1021/acschembio.1c00405. Epub 2021 Jul 26. ACS Chem Biol. 2021. PMID: 34309372 Free PMC article.
Inhibitors of DHHC family proteins.
Lan T, Delalande C, Dickinson BC. Lan T, et al. Among authors: delalande c. Curr Opin Chem Biol. 2021 Dec;65:118-125. doi: 10.1016/j.cbpa.2021.07.002. Epub 2021 Aug 28. Curr Opin Chem Biol. 2021. PMID: 34467875 Free PMC article. Review.
Early Castration in Horses Does Not Impact Osteoarticular Metabolism.
Rouge M, Legendre F, Elkhatib R, Delalande C, Cognié J, Reigner F, Barrière P, Deleuze S, Hanoux V, Galéra P, Bouraïma-Lelong H. Rouge M, et al. Among authors: delalande c. Int J Mol Sci. 2023 Nov 26;24(23):16778. doi: 10.3390/ijms242316778. Int J Mol Sci. 2023. PMID: 38069100 Free PMC article.
Molecular Glue Discovery: Current and Future Approaches.
Dewey JA, Delalande C, Azizi SA, Lu V, Antonopoulos D, Babnigg G. Dewey JA, et al. Among authors: delalande c. J Med Chem. 2023 Jul 27;66(14):9278-9296. doi: 10.1021/acs.jmedchem.3c00449. Epub 2023 Jul 12. J Med Chem. 2023. PMID: 37437222 Review.
108 results