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High-throughput screening discovers antifibrotic properties of haloperidol by hindering myofibroblast activation.
Rehman M, Vodret S, Braga L, Guarnaccia C, Celsi F, Rossetti G, Martinelli V, Battini T, Long C, Vukusic K, Kocijan T, Collesi C, Ring N, Skoko N, Giacca M, Del Sal G, Confalonieri M, Raspa M, Marcello A, Myers MP, Crovella S, Carloni P, Zacchigna S. Rehman M, et al. Among authors: del sal g. JCI Insight. 2019 Apr 18;4(8):e123987. doi: 10.1172/jci.insight.123987. eCollection 2019 Apr 18. JCI Insight. 2019. PMID: 30996132 Free PMC article.
A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action.
Campaner E, Rustighi A, Zannini A, Cristiani A, Piazza S, Ciani Y, Kalid O, Golan G, Baloglu E, Shacham S, Valsasina B, Cucchi U, Pippione AC, Lolli ML, Giabbai B, Storici P, Carloni P, Rossetti G, Benvenuti F, Bello E, D'Incalci M, Cappuzzello E, Rosato A, Del Sal G. Campaner E, et al. Among authors: del sal g. Nat Commun. 2017 Jun 9;8:15772. doi: 10.1038/ncomms15772. Nat Commun. 2017. PMID: 28598431 Free PMC article.
Author Correction: Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth.
Tombari C, Zannini A, Bertolio R, Pedretti S, Audano M, Triboli L, Cancila V, Vacca D, Caputo M, Donzelli S, Segatto I, Vodret S, Piazza S, Rustighi A, Mantovani F, Belletti B, Baldassarre G, Blandino G, Tripodo C, Bicciato S, Mitro N, Del Sal G. Tombari C, et al. Among authors: del sal g. Nat Commun. 2023 Nov 6;14(1):7129. doi: 10.1038/s41467-023-43018-3. Nat Commun. 2023. PMID: 37932286 Free PMC article. No abstract available.
Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth.
Tombari C, Zannini A, Bertolio R, Pedretti S, Audano M, Triboli L, Cancila V, Vacca D, Caputo M, Donzelli S, Segatto I, Vodret S, Piazza S, Rustighi A, Mantovani F, Belletti B, Baldassarre G, Blandino G, Tripodo C, Bicciato S, Mitro N, Del Sal G. Tombari C, et al. Among authors: del sal g. Nat Commun. 2023 Oct 25;14(1):6777. doi: 10.1038/s41467-023-42458-1. Nat Commun. 2023. PMID: 37880212 Free PMC article.
p73 as a pharmaceutical target for cancer therapy.
Bisso A, Collavin L, Del Sal G. Bisso A, et al. Among authors: del sal g. Curr Pharm Des. 2011;17(6):578-90. doi: 10.2174/138161211795222667. Curr Pharm Des. 2011. PMID: 21391908 Free PMC article. Review.
Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.
Rustighi A, Zannini A, Tiberi L, Sommaggio R, Piazza S, Sorrentino G, Nuzzo S, Tuscano A, Eterno V, Benvenuti F, Santarpia L, Aifantis I, Rosato A, Bicciato S, Zambelli A, Del Sal G. Rustighi A, et al. Among authors: del sal g. EMBO Mol Med. 2014 Jan;6(1):99-119. doi: 10.1002/emmm.201302909. Epub 2013 Dec 15. EMBO Mol Med. 2014. PMID: 24357640 Free PMC article.
153 results