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Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations.
Jafari N, Del Rio J, Akimoto M, Byun JA, Boulton S, Moleschi K, Alsayyed Y, Swanson P, Huang J, Martinez Pomier K, Lee C, Wu J, Taylor SS, Melacini G. Jafari N, et al. Among authors: del rio j. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2024716118. doi: 10.1073/pnas.2024716118. Proc Natl Acad Sci U S A. 2021. PMID: 34006641 Free PMC article.
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.
Baffi TR, Lordén G, Wozniak JM, Feichtner A, Yeung W, Kornev AP, King CC, Del Rio JC, Limaye AJ, Bogomolovas J, Gould CM, Chen J, Kennedy EJ, Kannan N, Gonzalez DJ, Stefan E, Taylor SS, Newton AC. Baffi TR, et al. Among authors: del rio jc. Sci Signal. 2021 Apr 13;14(678):eabe4509. doi: 10.1126/scisignal.abe4509. Sci Signal. 2021. PMID: 33850054 Free PMC article.
Impairing hydrolase transport machinery prevents human melanoma metastasis.
Nordlinger A, Del Rio J, Parikh S, Thomas L, Parikh R, Vaknine H, Brenner R, Baschieri F, Robert A, Khaled M. Nordlinger A, et al. Among authors: del rio j. Commun Biol. 2024 May 15;7(1):574. doi: 10.1038/s42003-024-06261-y. Commun Biol. 2024. PMID: 38750105 Free PMC article.
miR-519a-3p, found to regulate cellular prion protein during Alzheimer's disease pathogenesis, as a biomarker of asymptomatic stages.
Jácome D, Cotrufo T, Andrés-Benito P, Lidón L, Martí E, Ferrer I, Del Río JA, Gavín R. Jácome D, et al. Among authors: del rio ja. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 21;1870(5):167187. doi: 10.1016/j.bbadis.2024.167187. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38653354 Free article.
699 results