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In central obesity, weight loss restores platelet sensitivity to nitric oxide and prostacyclin.
Obesity (Silver Spring). 2010 Apr;18(4):788-97. doi: 10.1038/oby.2009.302. Epub 2009 Oct 15.
Obesity (Silver Spring). 2010.
PMID: 19834474
Free article.
Clinical Trial.
Resistance to the nitric oxide/cyclic guanosine 5'-monophosphate/protein kinase G pathway in vascular smooth muscle cells from the obese Zucker rat, a classical animal model of insulin resistance: role of oxidative stress.
Russo I, Del Mese P, Doronzo G, Mattiello L, Viretto M, Bosia A, Anfossi G, Trovati M.
Russo I, et al. Among authors: del mese p.
Endocrinology. 2008 Apr;149(4):1480-9. doi: 10.1210/en.2007-0920. Epub 2007 Dec 13.
Endocrinology. 2008.
PMID: 18079207
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Platelet resistance to the antiaggregatory cyclic nucleotides in central obesity involves reduced phosphorylation of vasodilator-stimulated phosphoprotein.
Russo I, Del Mese P, Doronzo G, De Salve A, Secchi M, Trovati M, Anfossi G.
Russo I, et al. Among authors: del mese p.
Clin Chem. 2007 Jun;53(6):1053-60. doi: 10.1373/clinchem.2006.076208. Epub 2007 Apr 26.
Clin Chem. 2007.
PMID: 17463178
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Sodium azide, a bacteriostatic preservative contained in commercially available laboratory reagents, influences the responses of human platelets via the cGMP/PKG/VASP pathway.
Russo I, Del Mese P, Viretto M, Doronzo G, Mattiello L, Trovati M, Anfossi G.
Russo I, et al. Among authors: del mese p.
Clin Biochem. 2008 Mar;41(4-5):343-9. doi: 10.1016/j.clinbiochem.2007.10.012. Epub 2007 Nov 7.
Clin Biochem. 2008.
PMID: 18022387
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Role of NMDA receptor in homocysteine-induced activation of mitogen-activated protein kinase and phosphatidyl inositol 3-kinase pathways in cultured human vascular smooth muscle cells.
Doronzo G, Russo I, Del Mese P, Viretto M, Mattiello L, Trovati M, Anfossi G.
Doronzo G, et al. Among authors: del mese p.
Thromb Res. 2010 Feb;125(2):e23-32. doi: 10.1016/j.thromres.2009.08.015. Epub 2009 Sep 18.
Thromb Res. 2010.
PMID: 19766294
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